Justin R. Bryant DO, MBA, CWSP , Peter Andrade DO , Raymond T. Hajjar DO , Christopher R. Lumley DO , Kongkrit Chaiyasate MD
{"title":"Malleolar Ulceration Induced by Hydroxyurea Therapy for Chronic Eosinophila","authors":"Justin R. Bryant DO, MBA, CWSP , Peter Andrade DO , Raymond T. Hajjar DO , Christopher R. Lumley DO , Kongkrit Chaiyasate MD","doi":"10.1016/j.jccw.2016.12.001","DOIUrl":null,"url":null,"abstract":"<div><p><span>A 59-year-old African American female presented to a plastic surgery office in consultation for a very painful non-healing wound of her right lateral malleolus. An incisional biopsy was performed and ultimately a diagnosis of hydroxyurea-induced </span>ulcer<span> was concluded. Descriptions of this entity are rare in the surgical and wound care professional literature. This diagnosis does appear in the hematology/oncology literature; however, these practitioners may not be the first to examine a patient with the development of such an ulcer. This article presents the pathophysiology and clinical presentation of hydroxyurea-induced ulceration as well as the characteristics of hydroxyurea-induced ulceration in addition to the case study.</span></p></div>","PeriodicalId":90358,"journal":{"name":"The journal of the American College of Clinical Wound Specialists","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jccw.2016.12.001","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The journal of the American College of Clinical Wound Specialists","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2213510316300720","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
A 59-year-old African American female presented to a plastic surgery office in consultation for a very painful non-healing wound of her right lateral malleolus. An incisional biopsy was performed and ultimately a diagnosis of hydroxyurea-induced ulcer was concluded. Descriptions of this entity are rare in the surgical and wound care professional literature. This diagnosis does appear in the hematology/oncology literature; however, these practitioners may not be the first to examine a patient with the development of such an ulcer. This article presents the pathophysiology and clinical presentation of hydroxyurea-induced ulceration as well as the characteristics of hydroxyurea-induced ulceration in addition to the case study.