Highlights from the 3rd international HIV/viral hepatitis Co-infection meeting - HIV/viral hepatitis: improving diagnosis, antiviral therapy and access.

Hepatology, medicine and policy Pub Date : 2017-04-20 eCollection Date: 2017-01-01 DOI:10.1186/s41124-017-0025-0
Tongai G Maponga, Rachel Matteau Matsha, Sébastien Morin, Andrew Scheibe, Tracy Swan, Isabelle Andrieux-Meyer, C Wendy Spearman, Marina B Klein, Jürgen Kurt Rockstroh
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引用次数: 5

Abstract

The International AIDS Society convened the 3rd International HIV/Viral Hepatitis Co-Infection Meeting on 17 July 2016 as part of the pre-conference program preceding the 21st International AIDS Conference held in Durban, South Africa. The meeting brought together a diversity of scientific, technical and community interests to discuss opportunities and challenges for increased prevention, diagnosis and treatment of viral hepatitis in people living with HIV, particularly in low- and middle-income settings. The objectives of the meeting were:i.To review the latest therapeutic developments in viral hepatitis;ii.To identify challenges such as high cost of medications for hepatitis C virus (HCV) and risk of developing viral resistance, and successes, such as the provision of HCV treatment in community-based settings, movements to reduce drug costs and increasing access, in relation to scaling up diagnosis, screening, antiviral treatment and prevention of viral hepatitis;iii.To advance the agenda for elimination of viral hepatitis as a public health problem. Discussions centred around the six key interventions outlined by the World Health Organization Global Health Sector Strategy on Viral Hepatitis 2016-2021: hepatitis B virus (HBV) vaccination (including birth dose); safe injection practices plus safe blood; harm reduction among people who inject drugs; safer sex practices; hepatitis B treatment; and hepatitis C cure. This article summarizes the main issues and findings discussed during the pre-conference meeting. One of the recommendations from the meeting delegates is universal implementation of birth dose vaccination for HBV without further delay to prevent mother-to-child transmission of infection. There is also the need to implement screening and treatment of hepatitis among pregnant women. A call was made for concerted efforts to be put together by all stakeholders towards addressing some of the structural barriers, including criminalization of drug use, discrimination and stigma that people living with viral hepatitis face. Finally, the need for greater advocacy was highlighted to enable access to therapy of viral hepatitis at lower cost than currently prevails. Implementation of these resolutions will help in achieving the target of eliminating viral hepatitis as a public health threat.

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第三届国际艾滋病毒/病毒性肝炎合并感染会议的亮点-艾滋病毒/病毒性肝炎:改进诊断、抗病毒治疗和可及性。
国际艾滋病协会于2016年7月17日召开了第三次国际艾滋病毒/病毒性肝炎合并感染会议,作为在南非德班举行的第21届国际艾滋病大会之前的会前规划的一部分。会议汇集了各种科学、技术和社区利益,讨论加强艾滋病毒感染者,特别是在低收入和中等收入环境中预防、诊断和治疗病毒性肝炎的机遇和挑战。会议的目标是:1。回顾病毒性肝炎的最新治疗进展;二、确定各种挑战,例如治疗丙型肝炎病毒的药物费用高和产生病毒耐药性的风险,以及在扩大病毒性肝炎的诊断、筛查、抗病毒治疗和预防方面取得的成功,例如在社区环境中提供丙型肝炎治疗,采取行动降低药物成本和增加可及性;推进消除作为公共卫生问题的病毒性肝炎的议程。讨论围绕世界卫生组织2016-2021年全球卫生部门病毒性肝炎战略概述的六项关键干预措施展开:乙型肝炎病毒(HBV)疫苗接种(包括出生剂量);安全注射方法和安全血液;减少注射毒品者的伤害;安全性行为;乙型肝炎治疗;丙型肝炎治愈。本文总结了会前会议讨论的主要问题和结果。会议代表提出的建议之一是不再拖延地普遍实施出生剂量乙肝疫苗接种,以防止母婴感染传播。还需要对孕妇进行肝炎筛查和治疗。会议呼吁所有利益攸关方共同努力,解决一些结构性障碍,包括病毒性肝炎患者面临的吸毒犯罪化、歧视和污名化。最后,强调有必要加大宣传力度,使人们能够以比目前更低的费用获得病毒性肝炎治疗。执行这些决议将有助于实现消除病毒性肝炎这一公共卫生威胁的目标。
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Correlates of hepatitis B awareness and disease-specific knowledge among pregnant women in Northern and Central Uganda: a cross-sectional study. Correction to: Hepatology, Medicine and Policy: Articles with DOIs 10.1186/s41124-016-0014-8, 10.1186/s41124-016-0013-9 and 10.1186/s41124-016-0012-x. Strategies for achieving viral hepatitis C micro-elimination in the Netherlands. Erratum: Publisher Correction to Hepatology, Medicine and Policy: Articles with DOIs 10.1186/s41124-017-0024-1, 10.1186/s41124-017-0025-0, 10.1186/s41124-017-0026-z and 10.1186/s41124-017-0027-y. Seroprevalence of hepatitis B and C in Nepal: a systematic review (1973-2017).
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