Cyberlindnera jadinii (teleomorph Candida utilis) candidaemia in a patient with aplastic anaemia: a case report.

JMM case reports Pub Date : 2018-07-10 eCollection Date: 2018-08-01 DOI:10.1099/jmmcr.0.005160

Pauline Treguier, Marion David, Gilles Gargala, Vincent Camus, Aspasia Stamatoullas, Anne-Lise Menard, Pascal Lenain, Nathalie Contentin, Emilie Lemasle, Helene Lanic, Hervé Tilly, Fabrice Jardin, Stéphane Lepretre

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引用次数: 9

Abstract

Introduction: We present what is believed to be the first report of candidaemia caused by Cyberlindnera (Pichia) jadinii (teleomorph of Candida utilis) in a patient with an aplastic anaemia.

Case presentation: The patient, a 21-year-old male, presented with hepatic cytolysis, cutaneous and pulmonary involvement, and septic shock. Cyberlindnera jadinii was identified by aerobic blood culture and MS. The patient initially received multiple and combined antifungal therapy, but continued to have persistent skin lesions and fever. He was successfully treated by emergency haploidentical haematopoietic stem cell transplantation, combined with triple antifungal therapy and supportive care.

Conclusion: Cyberlindnera jadinii, teleomorph of Candida utilis, which is not usually invasive, can lead to an opportunistic invasive infection in unhealthy adult patients. For treatment of the invasive candida infection, it is necessary to combine antifungal therapy and supportive care.

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再生障碍性贫血患者念珠菌血症1例报告。

简介:我们提出了被认为是由念珠菌(假丝酵母的远变形)在再生障碍性贫血患者引起念珠菌血症的第一份报告。病例介绍:患者，21岁男性，表现为肝细胞溶解，皮肤和肺部受累，感染性休克。通过有氧血培养和ms鉴定出jadinii，患者最初接受了多种和联合抗真菌治疗，但持续出现皮肤损伤和发烧。通过紧急单倍体造血干细胞移植，结合三联抗真菌治疗和支持性护理，成功治疗。结论:利用念珠菌的远变形念珠菌(Cyberlindnera jadinii)通常不具有侵袭性，但在不健康的成人患者中可导致机会性侵袭性感染。侵袭性念珠菌感染的治疗应结合抗真菌治疗和支持性护理。

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