Analysis of Incidence and Outcome Predictors for Patients Admitted to US Hospitals with Acetabular Fractures from 1990 to 2010.

Matthew J Best, Leonard T Buller, Stephen M Quinnan
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引用次数: 13

Abstract

The incidence of acetabular fractures and associated in-hospital complication rates in the United States are poorly defined. Studies evaluating predictors of outcome for isolated acetabular fractures are weakly generalizable due to small sample sizes or the inclusion of all types of pelvic fractures. This study sought to analyze trends in acetabular fractures and associated complications in the US using the largest and most recent national dataset available. The National Hospital Discharge Survey was queried to identify all patients admitted to US hospitals with acetabular fractures between 1990 and 2010. A representative cohort of 497,389 patients was identified, and multivariable logistic regression was used to identify independent predictors of mortality, adverse events, requirement of blood transfusion, and operative treatment with open reduction and internal fixation (ORIF). Between 1990 and 2010, the population-adjusted incidence of acetabular fractures increased from 7.8 to 9.5/100,000 capita (P < .001). Mortality declined from 5.9% to 0.4% (P < .001), paralleling an increase in the proportion of patients treated with ORIF (12.6%-20.4%, P < .001), which was the variable associated with the lowest odds of mortality. Surgical intervention was associated with higher odds of adverse events and a requirement for blood transfusion. The average in-hospital length of stay decreased from 17.0 days to 10.3 days (P < .001). This study provides the largest and most comprehensive epidemiologic analysis of acetabular fractures in the US. Knowledge of the increasing incidence of acetabular fractures and prognostic factors associated with poor outcomes may improve outcomes.

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1990 - 2010年美国医院髋臼骨折患者发病率及预后预测因素分析
在美国,髋臼骨折的发生率和相关的住院并发症发生率尚不明确。评估孤立性髋臼骨折预后预测因素的研究由于样本量小或纳入了所有类型的骨盆骨折,其通用性较弱。本研究试图利用最大和最新的国家数据集分析美国髋臼骨折及相关并发症的趋势。国家医院出院调查被询问,以确定1990年至2010年期间美国医院收治的所有髋臼骨折患者。确定了497,389例患者的代表性队列,并使用多变量logistic回归来确定死亡率、不良事件、输血需求和切开复位内固定手术治疗(ORIF)的独立预测因子。1990 - 2010年,人口调整后的髋臼骨折发生率从7.8 /10万人上升到9.5/10万人(P < 0.001)。死亡率从5.9%下降到0.4% (P < .001),与ORIF治疗的患者比例增加(12.6%-20.4%,P < .001)平行,这是与最低死亡率相关的变量。手术干预与较高的不良事件发生率和输血需求相关。平均住院时间由17.0天降至10.3天(P < 0.001)。这项研究提供了美国髋臼骨折最大和最全面的流行病学分析。了解髋臼骨折发生率的增加以及与预后不良相关的预后因素可能会改善预后。
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