Improved seizure control and regaining cognitive milestones after vagus nerve stimulation revision surgery in Lennox–Gastaut syndrome

Hilde M. Braakman , Joke Creemers , Danny M. Hilkman , Sylvia Klinkenberg , Suzanne M. Koudijs , Mariette Debeij-van Hall , Erwin M. Cornips
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引用次数: 4

Abstract

We report a child with Lennox–Gastaut syndrome with an increase in seizure frequency and loss of psychomotor skills due to a disintegrated cervical VNS lead, not detected during standard device monitoring. The lead was completely removed and replaced by a new 303 lead on the same nerve segment. After reinitiating VNS, side effects forced us to switch it off, resulting in immediate seizure recurrence. EEG recording demonstrated a non-convulsive status epilepticus that was halted by reinitiating VNS therapy. Thereafter, he remained seizure free for eight months, and regained psychomotor development.

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lenox - gastaut综合征迷走神经刺激改良手术后癫痫控制改善和认知里程碑恢复
我们报告了一个患有lenox - gastaut综合征的儿童,由于颈VNS导联解体,癫痫发作频率增加,精神运动技能丧失,在标准设备监测中未发现。铅被完全移除,在同一神经段上用新的303铅代替。重新启动迷走神经刺激后,副作用迫使我们关闭了它,导致癫痫立即复发。脑电图记录显示非惊厥性癫痫持续状态,通过重新启动VNS治疗停止。此后,他8个月没有癫痫发作,并恢复了精神运动发育。
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