Saline Infusion Sonography Can Improve Outcome in Subsequent ICSI Cycles When No Intrauterine Pathology Is Detected.

IF 0.2 4区医学 Q4 Medicine 生殖医学杂志 Pub Date : 2016-09-01

Sefa Kelekci, Gokhan Ciragil, Burak Yücel, Servet Gencdal, Emre Destegul, Orcun Ozdemir

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引用次数: 0

Abstract

Objective: To analyze the benefits of saline infusion sonography (SIS).due to its endometrial injury effect on outcomes of subsequent intracytoplasmic sperm injection (ICSI) cycles.

Study design: This study is a retrospective anal- ysis of 398 patients under- going ICSI cycles. The bio- chemical and clinical preg- nancy rates of 45 patients who underwent SIS prior to starting an ICSI cycle were compared to those of controls.

Results: Endometrial thickness was significantly higher in patients who underwent SIS (p=0.016). The biochemical pregnancy rate was statistically significant- ly higher in the SIS group than in the control group (p=0.040). The clinical pregnancy rate was 55.56% in patients who underwent SIS, while it was only 39.09% in the control group. The difference was statistically sig- nificant (p=0.037).

Conclusion: .SIS can be used to assess the endome- trial cavity prior to ICSI cycle; moreover, SIS might be associated with improved outcomes when no intrauterine pathology is detected. Confirmation of this finding via future robust randomized trials is needed and would be useful to further guide clinical practice.

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当没有发现宫内病理时，生理盐水输注超声检查可以改善后续ICSI周期的预后。

目的:分析生理盐水输注超声(SIS)的优点。由于子宫内膜损伤对随后的卵胞浆内单精子注射(ICSI)周期的结果有影响。研究设计:本研究对398例进行ICSI周期的患者进行回顾性分析。将45例在开始ICSI周期前接受SIS的患者的生化和临床妊娠率与对照组进行比较。结果:SIS组子宫内膜厚度明显增高(p=0.016)。SIS组生化妊娠率显著高于对照组(p=0.040)。SIS患者的临床妊娠率为55.56%，而对照组仅为39.09%。差异有统计学意义(p=0.037)。结论:在ICSI循环前，sis可用于评估内膜试验腔;此外，当未发现宫内病理时，SIS可能与预后改善有关。需要通过未来可靠的随机试验来证实这一发现，这将有助于进一步指导临床实践。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

生殖医学杂志医学-妇产科学

自引率

0.00%

发文量

6427

审稿时长

6-12 weeks

期刊介绍： The Journal of Reproductive Medicine® has been the essential tool of Obstetricians and Gynecologists since 1968. As a highly regarded professional journal and the official periodical of six medical associations, JRM® brings timely and relevant information on the latest procedures and advances in the field of reproductive medicine. Published bimonthly, JRM® contains peer-reviewed articles and case reports submitted by top specialists. Common topics include research, clinical practice, and case reports related to general obstetrics and gynecology, infertility, female cancers, gynecologic surgery, contraception, and medical education.