A Comparative Single-Blind Randomized Controlled Trial With Language Training in People With Mild Cognitive Impairment.

IF 2.7 4区医学 Q2 CLINICAL NEUROLOGY American Journal of Alzheimers Disease and Other Dementias Pub Date : 2019-05-01 Epub Date: 2018-12-05 DOI:10.1177/1533317518813554

Eleni Poptsi, Ioulietta Lazarou, Nefeli Markou, Maria Vassiloglou, Evdokia Nikolaidou, Alexandra Diamantidou, Vassiliki Siatra, Elina Karathanassi, Anastasios Karakostas, Fotini Kounti Zafeiropoulou, Thrasyvoulos Tsiatsos, Magda Tsolaki

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Abstract

Background: Although cognitive training is effective for people with mild cognitive impairment (MCI), it is not clear which format is more effective.

Objective: To compare the effectiveness of the same language programs when carried out via computer, paper/pencil and orally in people with MCI.

Methods: Seventy-one participants with MCI were randomly classified in 3 experimental and 2 control groups. The experimental groups attended 48 sessions of language training for 6 months. The control groups attended either unstructured sessions or they were on waiting list.

Results: Mixed measures analysis of variance, at the follow-up, showed a significant cognitive abilities improvement among the experimental versus control groups. At the end of the language training, the 3 groups presented improvement in cognitive abilities and daily function, while the control groups remained at the same performance level.

Conclusion: All 3 cognitive language training methods were equally significantly effective.

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在轻度认知障碍患者中开展语言训练的单盲随机对照对比试验。

背景：尽管认知训练对轻度认知障碍（MCI）患者有效，但哪种形式更有效尚不清楚：方法：将 71 名 MCI 患者随机分为 3 个实验组和 1 个对照组：方法：71 名 MCI 患者被随机分为 3 个实验组和 2 个对照组。实验组参加为期 6 个月的 48 节语言训练课。结果：混合测量方差分析显示，实验组和对照组的语言表达能力均高于对照组：混合计量方差分析显示，在随访中，实验组和对照组的认知能力都有显著提高。在语言培训结束时，3 个实验组的认知能力和日常功能都有所提高，而对照组则保持在同一水平：结论：三种认知语言训练方法都同样有效。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

American Journal of Alzheimers Disease and Other Dementias GERIATRICS & GERONTOLOGY-CLINICAL NEUROLOGY

CiteScore

5.40

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： American Journal of Alzheimer''s Disease and other Dementias® (AJADD) is for professionals on the frontlines of Alzheimer''s care, dementia, and clinical depression--especially physicians, nurses, psychiatrists, administrators, and other healthcare specialists who manage patients with dementias and their families. This journal is a member of the Committee on Publication Ethics (COPE).