Relationships Between Cognitive Dysfunction and Health-Related Quality of Life Among Older Persons in Taiwan: A Nationwide Population-Based Survey.

IF 2.7 4区医学 Q2 CLINICAL NEUROLOGY American Journal of Alzheimers Disease and Other Dementias Pub Date : 2019-02-01 Epub Date: 2018-12-05 DOI:10.1177/1533317518813548

Hsin-Yun Liu, Wen-Che Tsai, Ming-Jang Chiu, Li-Yu Tang, Huey-Jane Lee, Yea-Ing L Shyu, Woan-Shyuan Wang

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Abstract

Background: To examine the relationships between cognitive dysfunction status and quality of life.

Methods: Secondary analysis of a nationwide population-based survey (≥65 years) in Taiwan. The 5-dimension EuroQoL questionnaire (EQ-5D) was completed by 10 013 participants.

Results: Participants with mild cognitive impairment (MCI; odds ratio = 4.88), very mild dementia (VMD; 7.96), or dementia (32.85) were more likely than those with normal cognition to report self-care problems. Participants with MCI (3.86), VMD (9.26), or dementia (31.61) were more likely to have usual-activity problems, and those with MCI (3.04), VMD (3.82), or dementia (9.23) were more likely to have mobility problems. Participants with MCI (2.10 and 2.14), VMD (2.77 and 2.18), or dementia (3.04 and 3.02) were more likely to report pain/discomfort and anxiety/depression.

Conclusion: Dementia was negatively associated with EQ-5D, especially self-care, usual activities, and mobility. Mild cognitive impairment or VMD was also negatively associated, with VMD more negatively associated. Developing interventions for patients with specific cognitive dysfunctions is critical.

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台湾老年人认知功能障碍与健康相关生活质量之间的关系：以全国人口为基础的调查。

背景：研究认知功能障碍状况与生活质量之间的关系：研究认知功能障碍状况与生活质量之间的关系：方法：对台湾一项全国性人口调查（≥65 岁）进行二次分析。10 013 名参与者填写了五维欧洲生活质量问卷（EQ-5D）：结果显示：轻度认知障碍（MCI；几率比=4.88）、极轻度痴呆（VMD；7.96）或痴呆（32.85）患者比认知正常者更有可能报告自我护理问题。患有 MCI（3.86）、VMD（9.26）或痴呆症（31.61）的参试者更有可能存在日常活动问题，而患有 MCI（3.04）、VMD（3.82）或痴呆症（9.23）的参试者更有可能存在行动问题。患有 MCI（2.10 分和 2.14 分）、VMD（2.77 分和 2.18 分）或痴呆症（3.04 分和 3.02 分）的参与者更有可能报告疼痛/不适和焦虑/抑郁：痴呆症与 EQ-5D 呈负相关，尤其是自理能力、日常活动能力和行动能力。轻度认知障碍或 VMD 也呈负相关，其中 VMD 的负相关程度更高。为有特定认知功能障碍的患者制定干预措施至关重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

American Journal of Alzheimers Disease and Other Dementias GERIATRICS & GERONTOLOGY-CLINICAL NEUROLOGY

CiteScore

5.40

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： American Journal of Alzheimer''s Disease and other Dementias® (AJADD) is for professionals on the frontlines of Alzheimer''s care, dementia, and clinical depression--especially physicians, nurses, psychiatrists, administrators, and other healthcare specialists who manage patients with dementias and their families. This journal is a member of the Committee on Publication Ethics (COPE).