Wanessa Cardoso da Silva, Edione C Reis, Telma M Oshiro, Alessandra Pontillo
{"title":"Genetics of Inflammasomes.","authors":"Wanessa Cardoso da Silva, Edione C Reis, Telma M Oshiro, Alessandra Pontillo","doi":"10.1007/978-3-319-89390-7_14","DOIUrl":null,"url":null,"abstract":"<p><p>Mutations in inflammasome genes are responsible for rare monogenic and polygenic autoinflammatory diseases. On the other side, genetic polymorphisms in the same molecules contribute to the development of common multifactorial diseases (i.e., autoimmune diseases, cardiovascular pathologies, cancer). In this chapter we depicted the current knowledge about inflammasome genetics.</p>","PeriodicalId":36906,"journal":{"name":"Experientia supplementum (2012)","volume":"108 ","pages":"321-341"},"PeriodicalIF":0.0000,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/978-3-319-89390-7_14","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Experientia supplementum (2012)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/978-3-319-89390-7_14","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 1
Abstract
Mutations in inflammasome genes are responsible for rare monogenic and polygenic autoinflammatory diseases. On the other side, genetic polymorphisms in the same molecules contribute to the development of common multifactorial diseases (i.e., autoimmune diseases, cardiovascular pathologies, cancer). In this chapter we depicted the current knowledge about inflammasome genetics.
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