A SIMULATION MODEL OF THE OPEN PENETRATING SPINAL CORD TRAUMA WITH DURABLE PERSISTENCE OF BIOCOMPATIBLE FOREIGN BODY OF THE VERTEBRAL COLUMN CHANNELL. SYNDROME OF POSTTRAUMATIC SPASTICITY.

Abstract

Dynamics of the posttraumatic spasticity syndrome, a key component of spinal trauma, was investigated on simulation model of the open penetrating spinal cord (SC) trauma on adult male rats of aWistarline after half transection of the SC cross'section with its durable compression by biocompatible foreign body. Squeezing of the injured SC by foreign body potentiates formation of spasticity syndrome, and do not influence or restricts a severe pain syndrome occurrence. Reduction of the SC squeezing due to the foreign body elongation and reduction of its volume was accompanied by trustwor' thy rising of functional activity and the spasticity reduction in paretic extremity. Changes in activity of efferent chain of the movement system while formation of spasticity syn' drome in simulated trauma have occurred in both parts of SC ' in the injured one and in intact one as well, its severity did not correlate with presence of foreign body in zone of trauma.