[Effect of Needle Pricking Therapy on Rheological Indices and Efficacy for Infertile Patients with Varicocele].

中国中西医结合杂志 Pub Date : 2017-03-01
Dong Chen, Xiao He, Zhuo-Ming Chen, Lei Hu, Jian Zhong, Yan-Bo Hong, Jun Huang, Yue-Juan Zhang, Fu-Shi Zhen
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Abstract

Objective To observe the effect of needle pricking therapy on rheological indices and efficacy for infertile patients with varicocele (VC). Methods A total of 215 infertility patients with VC were assigned to the treatment group (109 cases, treated by needle pricking therapy) and the control group (106 cases, treated by drug therapy). Patients in the treatment group received CHEN's needle pricking therapy, once per week for a total of 10 times. Those in the control group took Guizhi Fuling Cap- sule (GFC), 0. 31g/pill, 3 pills each time, three times per day for 70 successive days. The diameter of VC, whole blood apparent viscosity, and plasma viscosity value were detected in the two groups after 75- day treatment. Sperm count, sperm motility rate, sperm motility, teratopermia rate, and other parame- ters were determined to evaluate the efficacy. Routines of blood, urine, and stool were detected. Renal and liver functions were examined to evaluate the safety. Results Compared with before treatment in the same group, the diameter of VC was narrowed in grade I and II patients of the two groups after treatment (P <0.05). The diameter of VC was obviously narrower in grade II patients of the treatment group after treatment (P <0. 01). Compared with before treatment in the same group, semen quality was improved in the two groups after treatment (P <0. 05,P <0.01). Besides, sperm density was reduced, sperm motility rate was elevated, spermatozoa with normal morphology was increased with longer fluidized time in the treatment group after treatment, which were all better than those of the control group (P <0.05). Compared with before treatment, whole blood apparent viscosity and plasma viscosity value both obviously decreased in the treatment group after treatment (P <0. 05). The total effective rate was better in the treatment group than in the control group (P <0. 05). Conclusion Needle pricking therapy could obviously improve blood flow and vasomotic elasticity of infertile patients with VC, lower plasma viscosity, thus promoting blood circulation and lowering VC.

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针刺治疗对不育精索静脉曲张患者流变学指标及疗效的影响。
目的观察针刺治疗对不育精索静脉曲张患者流变学指标及疗效的影响。方法将215例不孕症VC患者分为治疗组(109例,采用针刺治疗)和对照组(106例,采用药物治疗)。治疗组采用陈氏针刺疗法,每周1次,共10次。对照组服用桂枝茯苓胶囊(GFC);31g/片,每次3粒,每日3次,连续70天。两组治疗75 d后检测VC直径、全血表观黏度、血浆黏度值。测定精子数、精子活动力、精子活动力、畸胎儿率及其他参数以评价疗效。检测血、尿、便常规。检查肾脏和肝脏功能以评价安全性。结果与同组治疗前比较,两组ⅰ、ⅱ级患者治疗后VC直径均变窄(P < 0.05)
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