[Analysis of Clinical Medication Laws for 451 Patients with HIV Infection in a Real World].

Abstract

Objective To analyze clinical features and medication laws of patients with human immunodeficiency virus (HIV) infection. Methods Real world data based on Hospital Information System (HIS) were collected from 17 grade 3 hospitals across China from Jan.2006 to Dec.2011. Data of case his- tory in HIV infectors included their general information, features of AIDS, medications of Western drugs and Chinese herbs during hospitalization. Results Data of 451 patients with HIV infection were collected. A total of 261 patients had clear age record. Their age ranged between 18 and 65 [ accounting for 90. 4% (236/ 261 ) ], with an average age of 36. The ratio of male to female was 2. 8:1. They were hospitalized first at De- partment of Lemology (66. 96%), followed by Department of Respiration (8. 2%). They were admitted to hospital first at clinics (79. 6%), and accepted from Emergency Department (20. 18%). Most of them were admitted to hospital due to infectious diseases. Of them, tuberculosis occupied the top (8.29%), followed by bacterial pneumonia (6. 44%). Totally 349 patients had complete medication record. A total of 399 kinds of Western drugs and 80 kinds of Chinese patent medicines were used. The frequency of using antimicrobial drugs was the top (11. 86%), and Compound Sulfamethoxazole was mostly used in 120 cases (2. 81%). Of 80 kinds of Chinese patent medicines, heat clearing and detoxifying herbs were most often used (19. 27%), followed by antipyretics (10. 30%), tonics (8. 97%), and expectorant (7. 31%). Antimicrobial drugs combined heat clearing and detoxifying herbs were the most often seen in clinics. The 451 HIV infec- tors had steady condition after treated by Western drugs and Chinese herbs. The improvement rate reached 51. 33%. Conclusion Antimicrobial drugs were most often used in HIV patients. Heat clearing and detoxif- ying herbs were most often used in HIV patients. Antimicrobial drugs combined heat clearing and detoxif- ying herbs were most often seen in clinics for HIV patients.