Are there mortality risks for patients with epilepsy who use cannabis treatments as monotherapy?

Devon M. Kollmyer , Kyla E. Wright , Nicole M. Warner , Michael J. Doherty
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引用次数: 8

Abstract

Mortality associated with cannabis used for treatment of epilepsy is not well documented. We discuss two fatalities in the setting of epilepsy and self-determined therapy with cannabis (SDTC). One patient had probable sudden unexpected death in epilepsy, the second death was due to seizure-associated drowning. Both directed SDTC over conventional anti-seizure medications. Where recreational cannabis is legal, decisions to use cannabis are often self-directed and independent of physician advice of cannabis risks, in part because physicians may not be aware of the risk of SDTC. Further study of morbidity and mortality of SDTC in patients with epilepsy is needed.

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使用大麻作为单一疗法的癫痫患者是否存在死亡风险?
与用于治疗癫痫的大麻有关的死亡率没有很好的记录。我们讨论癫痫和大麻(SDTC)自我决定的治疗设置两个死亡。1例患者可能因癫痫猝死,2例患者因癫痫相关溺水死亡。两家公司都将SDTC置于常规抗癫痫药物之上。在娱乐性大麻合法的地方,使用大麻的决定往往是自主的,独立于医生关于大麻风险的建议,部分原因是医生可能不知道SDTC的风险。需要进一步研究SDTC在癫痫患者中的发病率和死亡率。
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