Forced normalization after turning off vagus nerve stimulation in Lennox–Gastaut syndrome

Sydney Lee , Alyssa Denton , Lady Diana Ladino , Karen Waterhouse , Aleksander Vitali , Jose Francisco Tellez-Zenteno
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引用次数: 6

Abstract

Forced normalization is the development of psychiatric symptoms in a patient experiencing remission of seizures. We present a case of Lennox Gastaut syndrome in which forced normalization developed after vagus nerve stimulation was stopped.

The patient had drug resistant epilepsy and failed anti-seizure drugs, vagus nerve stimulation, and a partial callosotomy.

The patient had multiple types of seizures including drop attacks, absences, and tonic–clonic seizures. He tried vagus nerve stimulation for two years without success. Forced normalization developed after the vagus nerve stimulator was turned off.

This is the first case to our knowledge to describe forced normalization after turning off the vagus nerve stimulator.

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lenox - gastaut综合征中关闭迷走神经刺激后的强迫正常化
强迫正常化是在经历癫痫发作缓解的患者中精神症状的发展。我们提出了一例Lennox Gastaut综合征,在迷走神经刺激停止后,强迫正常化发展。患者有耐药癫痫和失败的抗癫痫药物,迷走神经刺激和部分胼胝体切开术。患者有多种类型的癫痫发作,包括跌落发作、缺席和强直阵挛发作。他尝试了两年的迷走神经刺激,但没有成功。迷走神经刺激器关闭后,出现了强迫正常化。这是据我们所知的第一个在关闭迷走神经刺激器后描述强迫正常化的病例。
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