Idarucizumab in High-risk Thoracic Surgery.

IF 0.3 Q4 TRANSPLANTATION International Journal of Organ Transplantation Medicine Pub Date : 2018-01-01 Epub Date: 2018-05-01
R López-Vilella, J Sanz-Sánchez, I Sánchez-Lázaro, E Marques-Sule, J Rueda-Soriano, L Almenar-Bonet
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引用次数: 0

Abstract

Direct oral anticoagulants have suggested a favorable profile compared with vitamin K antagonists. However, the lack of treatment to reverse the effect of direct oral anticoagulants has limited its use in some patients who require rapid reversal of anticoagulation, as those included in the transplant waiting list. Idarucizumab is a recently approved drug to reverse the anticoagulant effect of dabigatran. However, the clinical experience when using this drug is scarce. Herein, we present a clinical case on anticoagulation reversal with idarucizumab to perform heart and lung transplantation in a patient with Eisenmenger syndrome.

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Idarucizumab在高危胸外科手术中的应用
与维生素K拮抗剂相比,直接口服抗凝剂的效果更好。然而,缺乏逆转直接口服抗凝剂效果的治疗方法,限制了它在一些需要快速逆转抗凝治疗的患者中的应用,如那些在移植等待名单中的患者。Idarucizumab是最近批准的一种逆转达比加群抗凝作用的药物。然而,临床使用该药的经验很少。在这里,我们提出了一个临床病例抗凝逆转用依达鲁珠单抗进行心肺移植患者艾森曼格综合征。
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来源期刊
CiteScore
1.60
自引率
0.00%
发文量
0
审稿时长
12 weeks
期刊介绍: The International Journal of Organ Transplantation Medicine (IJOTM) is a quarterly peer-reviewed English-language journal that publishes high-quality basic sciences and clinical research on transplantation. The scope of the journal includes organ and tissue donation, procurement and preservation; surgical techniques, innovations, and novelties in all aspects of transplantation; genomics and immunobiology; immunosuppressive drugs and pharmacology relevant to transplantation; graft survival and prevention of graft dysfunction and failure; clinical trials and population analyses in the field of transplantation; transplant complications; cell and tissue transplantation; infection; post-transplant malignancies; sociological and ethical issues and xenotransplantation.
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