Qian Wang, Xiu-Jin Meng, Hai-Tao Tang, Ying-Ming Pan, Wen-Gui Duan and Mu-Xue He
{"title":"Electrochemically driven α-thiocarbamylation via a dehydrocoupling strategy of β-ketoesters with amines and CS2†","authors":"Qian Wang, Xiu-Jin Meng, Hai-Tao Tang, Ying-Ming Pan, Wen-Gui Duan and Mu-Xue He","doi":"10.1039/D2GC04544C","DOIUrl":null,"url":null,"abstract":"<p >The development of atom- and step-economical methods for converting hazardous CS<small><sub>2</sub></small> into harmless chemicals is a challenging endeavor. Herein, we disclose a feasible strategy for the electrochemical dehydrogenative coupling of CS<small><sub>2</sub></small> and amines with β-ketoesters, which leads to dithiocarbamate intermediates in the presence of bases. In addition, inexpensive starting materials, broad substrate scope, and compatibility with natural product moieties make this efficient and sustainable reaction practical.</p>","PeriodicalId":78,"journal":{"name":"Green Chemistry","volume":" 7","pages":" 2572-2576"},"PeriodicalIF":9.3000,"publicationDate":"2023-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Green Chemistry","FirstCategoryId":"92","ListUrlMain":"https://pubs.rsc.org/en/content/articlelanding/2023/gc/d2gc04544c","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
The development of atom- and step-economical methods for converting hazardous CS2 into harmless chemicals is a challenging endeavor. Herein, we disclose a feasible strategy for the electrochemical dehydrogenative coupling of CS2 and amines with β-ketoesters, which leads to dithiocarbamate intermediates in the presence of bases. In addition, inexpensive starting materials, broad substrate scope, and compatibility with natural product moieties make this efficient and sustainable reaction practical.
期刊介绍：
Green Chemistry is a journal that provides a unique forum for the publication of innovative research on the development of alternative green and sustainable technologies. The scope of Green Chemistry is based on the definition proposed by Anastas and Warner (Green Chemistry: Theory and Practice, P T Anastas and J C Warner, Oxford University Press, Oxford, 1998), which defines green chemistry as the utilisation of a set of principles that reduces or eliminates the use or generation of hazardous substances in the design, manufacture and application of chemical products. Green Chemistry aims to reduce the environmental impact of the chemical enterprise by developing a technology base that is inherently non-toxic to living things and the environment. The journal welcomes submissions on all aspects of research relating to this endeavor and publishes original and significant cutting-edge research that is likely to be of wide general appeal. For a work to be published, it must present a significant advance in green chemistry, including a comparison with existing methods and a demonstration of advantages over those methods.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
