Ferulic Acid: A Promising Therapeutic Phytochemical and Recent Patents Advances.

IF 4.2 Q3 Pharmacology, Toxicology and Pharmaceutics Recent patents on inflammation & allergy drug discovery Pub Date : 2019-01-01 DOI:10.2174/1872213X13666190621125048
Ashun Chaudhary, Vivek S Jaswal, Sonika Choudhary, Sonika, Ajay Sharma, Vikas Beniwal, Hardeep S Tuli, Sanjeev Sharma
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引用次数: 73

Abstract

Background: Among the various phenolics metabolites, ferulic acid is considered as the promising mitigating, restorative and antioxidant agent. Ferulic acid is one of the most commonly found natural products in vegetables, for example, tomatoes, sweet corn, and in rice grain. Phytochemicals are utilized in the treatment of human ailments and these are derived from the dietary compounds.

Objective: The present review widely argued the calming restorative capability of ferulic acid alongside the scientific evidences and its proposed mechanism for activity. Furthermore, we provided the main practical points for the use of ferulic acid in oxidative damages during various diseases. Additionally, the relevant patents on ferulic acid with various therapeutic potential has been discussed.

Methods: The approach consisted of searching several resources, including theses, technical reports, web-based scientific databases such as publications on PubMed, ScienceDirect, Springer, PROTA, Google Scholar, and other allied databases. Thus, recent patent regarding the role of ferulic acid therapeutic potenitial has been discussed.

Results: One hundred and twenty references have been cited in the present review article. The cited references were found to be suitable and described the therapeutic application of ferulic acid thoroughly.

Conclusion: Ferulic acids are known to contrarily down-manage an assortment of extracellular and intrcelullular molecular targets related to infection movement. Various patents on ferulic acid based moieties have been accounted for from 2018. The ferulic acids have a wide scope of impacts against different infections like malignant growth, diabetes, cardiovascular and neurodegenerative diseases. The current review deals with the antioxidant property of ferulic acid and the recent patent describes the role of ferulic acid against human diseases.

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阿魏酸:一种很有前途的治疗植物化学物质及最新专利进展。
背景:在各种酚类代谢产物中,阿魏酸被认为是一种很有前途的缓解、恢复和抗氧化剂。阿魏酸是蔬菜中最常见的天然产物之一,例如西红柿、甜玉米和稻谷。植物化学物质用于治疗人类疾病,这些物质来源于膳食化合物。目的:综述阿魏酸的镇静恢复作用及其作用机制。此外,我们还提供了阿魏酸在各种疾病中氧化损伤的应用的主要实用要点。此外,还讨论了具有各种治疗潜力的阿魏酸的相关专利。方法:该方法包括搜索多种资源,包括论文、技术报告、基于网络的科学数据库,如PubMed、ScienceDirect、Springer、PROTA、Google Scholar和其他相关数据库。因此,最近的专利关于阿魏酸的治疗潜力的作用进行了讨论。结果:共引用文献120篇。发现所引用的文献均属合适,并对阿魏酸的治疗应用作了较为全面的描述。结论:阿魏酸与感染运动相关的细胞外和细胞内分子靶标具有相反的抑制作用。从2018年起,阿魏酸基部分的各种专利已被计算在内。阿魏酸对不同的感染有广泛的影响,如恶性生长、糖尿病、心血管和神经退行性疾病。本文综述了阿魏酸的抗氧化性能,最近的专利描述了阿魏酸对人类疾病的作用。
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来源期刊
CiteScore
3.90
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期刊介绍: Recent Patents on Inflammation & Allergy Drug Discovery publishes review articles by experts on recent patents in the field of inflammation and allergy drug discovery e.g. on novel bioactive compounds, analogs and targets. A selection of important and recent patents in the field is also included in the journal. The journal is essential reading for all researchers involved in inflammation and allergy drug design and discovery.
期刊最新文献
Meet Our Editorial Board Member Diagnosis of Allergic Reactions to Drugs Non-steroidal Anti-inflammatory Drugs Other Antimicrobial Drugs Biologics: Monoclonal Antibodies for Non-cancer Therapy, Cytokines, Fusion Proteins, Enzymes, and Hormones
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