Pre and Post-Operative Ph-Metry in Videolaparoscopic Surgery for Gastro Oesophageal Reflux Disease.

IF 1.1 Q4 MEDICINE, RESEARCH & EXPERIMENTAL Translational Medicine at UniSa Pub Date : 2019-01-12 eCollection Date: 2019-07-01
A Garzi, G Ardimento, U Ferrentino, S Brongo, R M Di Crescenzo, E Calabrò, M S Rubino, B Malamisura, E Clemente
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Abstract

Gastro-oesophageal reflux is common in children, especially in the first year of life, and it may be regarded as physiological. Good functioning of the lower oesophageal sphincter depends largely on the anatomical relationships between oesophagus, stomach and diaphragm hiatus. Relative immaturity of these structures in newborn babies and young children is a risk factor in reflux disease, which may result in a wide variety of typical and/or atypical symptoms and, sometimes, serious complications such as oesophagitis and stenosis. Reflux disease may be diagnosed and studied, basing on morphological and functional aspects and, since the advent of pH-metry, it is possible to personalise the therapeutic approach to children with reflux. Surgical treatment of reflux disease in children has recently been improved due to a mini-invasive surgical approach. Absolute indications are recurrent pneumonia, intractable pain due to oesophagitis and retarded growth, often in association with neurological impairment. In the last three years, 18 children with reflux disease underwent videolaparoscopic surgery in our department, 14 by the Nissen and 4 by the Toupet technique. Post-operative pH-metry always showed a reduction in exposure of the distal oesophagus to acid (integral of H+) and an improvement in oesophageal clearance (short refluxes percentage) indicative of good functioning of the gastro-oesophageal junction. PH-metry proved to be an invaluable technique for planning therapeutic strategy. In follow-up evaluations, it enabled us to monitor functioning of the gastro-oesophageal junction and to avoid other more difficult and invasive tests in patients with severe neurological impairment.

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胃食管反流病电视腹腔镜手术的术前和术后Ph-Metry。
胃食管反流在儿童中很常见,尤其是在出生的第一年,它可能被认为是生理性的。食管下括约肌的良好功能在很大程度上取决于食管、胃和膈肌裂孔之间的解剖关系。新生儿和幼儿的这些结构相对不成熟是反流病的一个危险因素,反流病可能会导致各种典型和/或非典型症状,有时还会导致食道炎和狭窄等严重并发症。反流性疾病可以根据形态学和功能方面进行诊断和研究,并且由于pH测量的出现,有可能对反流性儿童的治疗方法进行个性化。儿童反流性疾病的外科治疗最近由于一种微创手术方法而有所改进。绝对适应症是复发性肺炎、食道炎引起的顽固性疼痛和生长迟缓,通常与神经损伤有关。在过去的三年里,我科有18名患有反流疾病的儿童接受了视频腹腔镜手术,其中14名接受了Nissen手术,4名接受了Toupet技术。术后pH测量始终显示,食管远端暴露于酸的程度减少(H+积分),食管清除率提高(短回流百分比),表明胃-食管交界处功能良好。PH测定被证明是制定治疗策略的一项宝贵技术。在后续评估中,它使我们能够监测胃食管交界处的功能,并避免对严重神经损伤患者进行其他更困难和更具侵入性的测试。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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Translational Medicine at UniSa
Translational Medicine at UniSa MEDICINE, RESEARCH & EXPERIMENTAL-
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