[A Case of Aortic Graft Infection Due to Listeria monocytogenes Detected by Microarray-Based, Multiplexed, Automated Molecular Diagnosis System].

Mai Kodama, Masaki Nakanishi, Naohisa Fujita, Tomoya Inoue, Katsuhiko Oka, Keiichi Kanda, Hitoshi Yaku
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Abstract

A 80-year-old man was transferred to our hospital for hemoptysis caused by erosion(perforation) of thoracic aortic stent graft infection into the airway. Blood cultures on admission detected Gram-positive rods, and a microarray-based, multiplexed, automated molecular diagnosis instrument (Verigene® system) identified Listeria spp. Although Listeria monocytogenes is rare organism of stent graft infection, we were able to start appropriate antibiotic therapy on the second hospital day due to rapid identification of bacteria. Verigene® system is considered to be useful in severe infectious diseases including stent graft infections, even if the causative organism is rare.

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基于微阵列、多路复用、自动分子诊断系统检测一例单核细胞增生李斯特菌引起的主动脉移植感染。
一例80岁男性患者因胸主动脉支架植入术感染气道内侵蚀(穿孔)致咯血而转至我院。入院时的血液培养检测到革兰氏阳性棒,基于微阵列、多路、自动分子诊断仪器(Verigene®系统)检测到李斯特菌。尽管单核增生李斯特菌是支架感染的罕见菌,但由于细菌的快速鉴定,我们能够在住院的第二天开始适当的抗生素治疗。Verigene®系统被认为是有用的严重感染性疾病,包括支架移植感染,即使致病的有机体是罕见的。
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