Toxoplasma gondii And Neospora caninum In Brain Tissue Of Rodents In North-West Iran.

IF 1.7 Q2 VETERINARY SCIENCES Veterinary medicine (Auckland, N.Z.) Pub Date : 2019-12-20 eCollection Date: 2019-01-01 DOI:10.2147/VMRR.S224664
Naser Nazari, Saeedeh Shojaee, Mehdi Mohebali, Aref Teimouri, Keyghobad Ghadiri, Saber Raeghi, Mohammad Reza Shiee, Yousef Azarakhsh, Arezoo Bozorgomid
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引用次数: 5

Abstract

Purpose: Rodents live in proximity to humans and domestic animals. These creatures can serve as reservoir hosts for many zoonotic parasites; therefore, they increase the risk of human infections. The aim of this study was to investigate Toxoplasma gondii and Neospora caninum in rodents caught in Meshgin-Shahr District, Iran.

Patients and methods: In a cross-sectional study, brain samples were collected from 70 rodents caught in Meshgin-Shahr District during March and December 2015. The specimens were examined for exposure to T. gondii and N. caninum with molecular methods.

Results: Seventy rodents were caught, including 50 Meriones persicus, 11 Mus musculus and 9 Cricetulus migratorius. Thirty rodents were female and 40 were males. Using PCR (B1 gene), T. gondii was detected in 7.1% (5/70) of the rodents while N. caninum was not detected. The prevalence of Toxoplasma infection was higher in female rodents (4.28%) compared to male rodents (2.86%), but the difference was not significant.

Conclusion: The results showed a low risk of T. gondii and N. caninum among rodents. Finally, further research is needed to understand the role of these rodent species in the transmission of the above protozoan pathogens to humans and livestock in this area.

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伊朗西北部啮齿动物脑组织中的刚地弓形虫和犬新孢子虫。
目的:啮齿动物生活在人类和家畜附近。这些生物可以作为许多人畜共患寄生虫的宿主;因此,它们增加了人类感染的风险。本研究的目的是调查在伊朗Meshgin-Shahr地区捕获的啮齿动物中的刚地弓形虫和犬新孢子虫。患者和方法:在一项横断面研究中,收集了2015年3月至12月在Meshgin-Shahr区捕获的70只啮齿动物的脑样本。用分子方法检查标本是否暴露于弓形虫和犬奈瑟虫。结果:共捕获鼠类70只,其中灰鼠50只,小家鼠11只,迁徙鼠9只。其中雌性30只,雄性40只。PCR (B1基因)检测结果显示,7.1%(5/70)鼠中检出弓形虫,未检出犬奈虫。雌性鼠弓形虫感染率(4.28%)高于雄性鼠(2.86%),但差异不显著。结论:鼠间弓形虫和犬奈瑟虫感染风险较低。最后,需要进一步研究这些啮齿动物在该地区人类和牲畜中传播上述原生动物病原体的作用。
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