Lipophilic Antioxidants and Cognitive Function in the Elderly.

IF 2.3 Q3 NUTRITION & DIETETICS Nutrition and Metabolic Insights Pub Date : 2020-02-03 eCollection Date: 2020-01-01 DOI:10.1177/1178638820903300

Karen L Niemchick, Carla Riemersma, Grace A Lasker

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引用次数: 2

Abstract

Objective: To determine the relationship between blood serum lipophilic antioxidant levels and cognitive function (CF) in older adults aged 60 and above guided by the oxidative stress theory of aging.

Methods: Cross-sectional data from the National Health and Nutrition Examination Survey (n = 291) for older adults aged 60 and above were examined using Pearson correlation coefficient and multiple linear regression to determine whether blood serum antioxidant status predicted CF while controlling for age, sex, race, hypertension, smoking status, and body mass index.

Results: Alpha-tocopherol, retinyl palmitate, trans-lycopene, and retinyl stearate were all significantly correlated with CF. After controlling for covariates, α-tocopherol and retinyl palmitate were associated with CF. Age, sex, and current smoking status were significant predictors of CF.

Conclusions: The benefits of antioxidants in CF may be a part of nutritional recommendations which include α-tocopherol and retinyl palmitate for delay of CI, and subsequently a better quality of life.

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老年人的亲脂性抗氧化剂与认知功能。

目的:在氧化应激衰老理论指导下，探讨60岁及以上老年人血清亲脂性抗氧化剂水平与认知功能(CF)的关系。方法:采用Pearson相关系数和多元线性回归对291名60岁及以上老年人的全国健康与营养调查的横断面数据进行检验，在控制年龄、性别、种族、高血压、吸烟状况和体重指数的情况下，确定血清抗氧化水平是否预测CF。结果:α-生育酚、视黄醇棕榈酸酯、反式番茄红素和视黄醇硬脂酸酯均与CF显著相关。在控制协变量后，α-生育酚和视黄醇棕榈酸酯与CF相关。年龄、性别和当前吸烟状况是CF的显著预测因素。结论:CF的抗氧化剂的益处可能是营养推荐的一部分，包括α-生育酚和视黄醇棕榈酸酯可以延缓CI，并随后提高生活质量。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nutrition and Metabolic Insights NUTRITION & DIETETICS-

CiteScore

3.30

自引率

0.00%

发文量

审稿时长

8 weeks

期刊介绍： Nutrition and Metabolic Insights is a peer-reviewed, open-access online journal focusing on all aspects of nutrition and metabolism. This encompasses nutrition, including the biochemistry of metabolism, exercise and associated physical processes and also includes clinical articles that relate to metabolism, such as obesity, lipidemias and diabetes. It includes research at the molecular, cellular and organismal levels. This journal welcomes new manuscripts for peer review on the following topics: Nutrition, including the biochemistry of metabolism, Exercise and associated physical processes, Clinical articles that relate to metabolism, such as obesity, lipidemias and diabetes, Research at the molecular, cellular and organismal levels, Other areas of interest include gene-nutrient interactions, the effects of hormones, models of metabolic function, macronutrient interactions, outcomes of changes in diet, and pathophysiology.