Efficacy of strategies to increase participation in cervical cancer screening: GPs offering self-sampling kits for HPV testing versus recommendations to have a pap smear taken - A randomised controlled trial

E. Peeters , K. Cornet , D. Devroey , M. Arbyn
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引用次数: 9

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提高宫颈癌筛查参与策略的有效性:全科医生提供HPV检测自采样试剂盒与建议进行巴氏涂片检查-一项随机对照试验
背景:宫颈癌可以通过早期发现和治疗癌前病变来预防。比利时目前的筛查政策(3年宫颈抹片细胞学检查)覆盖了60%的目标人群。全科医生提供自我样本可以为目前未接受筛查的妇女克服障碍。方法:在2014年11月至2015年4月期间,年龄在25岁至64岁之间三年未做过子宫颈抹片检查并在佛兰德市咨询过全科医生的女性按1:1的比例分配到干预组和对照组,干预组的女性获得阴道自采样试剂盒,对照组的女性被鼓励预约由临床医生进行子宫颈抹片检查。结果:88名同意的女性被随机分组。自采样组45名女性中有35名(78%)参加了筛查,而对照组43名女性中有22名(51%)参加了筛查(p = 0.009)。在调整协变量(年龄类别、教育水平、自上次子宫颈抹片检查以来的时间间隔、过去的子宫颈抹片检查者)后,这一差异仍然显著。结论:全科医生提供自采样试剂盒,导致高参与率。更大规模的试验应该证实这种效果,并评估这种方法的可行性。作者还希望在致谢中包括以下一句话:“感谢AML实验室(比利时安特卫普)对自我样本进行免费HPV检测。”
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来源期刊
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审稿时长
14 weeks
期刊介绍: The official Journal of the International Papillomavirus Society Papillomavirus Research (PVR), the Journal of HPV and other Small DNA Tumor Viruses publishes innovative papers related to all aspects of papillomaviruses and other small DNA tumor viruses. The official journal of the International Papillomavirus Society, PVR is an open access publication that aims to bring together virologists, immunologists, epidemiologists and clinicians working in the booming field of HPV and animal papillomaviruses, polyomaviruses and other small DNA tumor viruses and their associated diseases, in order to foster and facilitate interdisciplinary communication. The journal welcomes original research articles, reviews, short communications, opinion articles and regional update reports on papillomaviruses and other tumor viruses in the following sections: a. Biology of papillomaviruses and related viruses from life cycle to cancer b. Epidemiology etiology and natural history studies c. Natural and induced immunity including vaccine research d. Intervention studies and strategies including i. Clinical studies and trials ii. HPV treatments iii. HPV vaccination programs iv. Diagnostics and screening e. Infection and disease prevention, modeling studies f. Guidelines and public health recommendations g. HPV Studies in special populations Regional and local studies on these viruses.
期刊最新文献
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