Surgical Outcomes of Type A Aortic Dissection at a Small-Volume Medical Center: Analysis according to the Extent of Surgery.

Chul Ho Lee, Jun Woo Cho, Jae Seok Jang, Tae Hong Yoon
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引用次数: 3

Abstract

Background: Despite progress in treatment, Stanford type A aortic dissection is still a life-threatening disease. In this study, we analyzed surgical outcomes in patients with Stanford type A aortic dissection according to the extent of surgery at Daegu Catholic University Medical Center.

Methods: We retrospectively analyzed 98 patients with Stanford type A aortic dissection who underwent surgery at our institution between January 2008 and June 2018. Of these patients, 82 underwent limited replacement (hemi-arch or ascending aortic replacement), while 16 patients underwent total arch replacement (TAR). We analyzed in-hospital mortality, postoperative complications, the overall 5-year survival rate, and the 5-year aortic event-free survival rate.

Results: The median follow-up time was 48 months (range, 1-128 months), with a completion rate of 85.7% (n=84). The overall in-hospital mortality rate was 8.2%: 6.1% in the limited replacement group and 18.8% in the TAR group (p=0.120). The overall 5-year survival rate was 78.8% in the limited replacement group and 81.3% in the TAR group (p=0.78). The overall 5-year aortic event-free survival rate was 85.3% in the limited replacement group and 88.9% in the TAR group (p=0.46).

Conclusion: The extent of surgery was not related to the rates of in-hospital mortality, complications, aortic events, or survival. Although this study was conducted at a small-volume center, the in-hospital mortality and 5-year survival rates were satisfactory.

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小容量医疗中心A型主动脉夹层手术效果:基于手术范围的分析
背景:尽管在治疗方面取得了进展,斯坦福A型主动脉夹层仍然是一种危及生命的疾病。在本研究中,我们根据大邱天主教大学医疗中心的手术范围,分析了斯坦福A型主动脉夹层患者的手术效果。方法:回顾性分析2008年1月至2018年6月在我院接受手术的98例斯坦福A型主动脉夹层患者。在这些患者中,82例接受了有限的置换术(半弓或升主动脉置换术),而16例接受了全弓置换术(TAR)。我们分析了住院死亡率、术后并发症、总5年生存率和5年无主动脉事件生存率。结果:中位随访时间48个月(范围1 ~ 128个月),完成率85.7% (n=84)。总体住院死亡率为8.2%:有限替代组为6.1%,TAR组为18.8% (p=0.120)。有限替代组的总5年生存率为78.8%,TAR组为81.3% (p=0.78)。有限置换术组5年无主动脉事件总生存率为85.3%,TAR组为88.9% (p=0.46)。结论:手术范围与住院死亡率、并发症、主动脉事件或生存率无关。虽然这项研究是在一个小容量的中心进行的,但住院死亡率和5年生存率令人满意。
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