Clinical Outcomes of Osteoarticular Extracorporeal Irradiated Autograft for Malignant Bone Tumor.

Q2 Medicine Sarcoma Pub Date : 2020-03-30 eCollection Date: 2020-01-01 DOI:10.1155/2020/9672093

Satoshi Takenaka, Nobuhito Araki, Takafumi Ueda, Shigeki Kakunaga, Yoshinori Imura, Ken-Ichiro Hamada, Hidetatsu Outani, Norifumi Naka, Akira Myoui, Hideki Yoshikawa

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引用次数: 8

Abstract

Methods: We retrospectively reviewed 33 patients who underwent osteoarticular ECIA after bone tumor resection from 1988 to 2014. We investigated complications, radiographic changes by the International Society of Limb Salvage graft evaluation criteria, and functional outcomes according to the Musculoskeletal Tumor Society scoring system.

Results: Fifteen patients were reoperated upon due to infection (n = 9), protruding fixation implant (n = 4), or fracture of the grafted bone (n = 2). The average radiographic evaluation score was 66.4%, and the median functional score was 23 (77%). The radiographic score for the proximal humerus or proximal tibia was lower than that for the other locations. The functional score was not different among the autograft sites but was related to the radiographic score.

Conclusion: Although osteoarticular ECIA is one of the reasonable surgical options for patients with tumors for which reliable prostheses are not available, we do not recommend osteoarticular ECIA as a routine procedure because of high complication rate.

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自体骨关节体外辐照移植治疗恶性骨肿瘤的临床疗效。

方法:回顾性分析1988 ~ 2014年33例骨肿瘤切除术后行骨关节ECIA的患者。我们根据国际残肢移植评估标准调查了并发症、影像学变化，并根据肌肉骨骼肿瘤协会评分系统调查了功能结果。结果:15例患者因感染(n = 9)、内固定物突出(n = 4)或移植物骨折(n = 2)再次手术。平均影像学评分为66.4%，中位功能评分为23分(77%)。肱骨近端或胫骨近端x线评分低于其他部位。功能评分在自体移植物部位间无差异，但与影像学评分相关。结论:虽然骨关节ECIA是无法获得可靠假体的肿瘤患者的合理手术选择之一，但由于并发症发生率高，我们不建议将骨关节ECIA作为常规手术。

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来源期刊

Sarcoma Medicine-Radiology, Nuclear Medicine and Imaging

CiteScore

5.00

自引率

0.00%

发文量

审稿时长

14 weeks

期刊介绍： Sarcoma is dedicated to publishing papers covering all aspects of connective tissue oncology research. It brings together work from scientists and clinicians carrying out a broad range of research in this field, including the basic sciences, molecular biology and pathology and the clinical sciences of epidemiology, surgery, radiotherapy and chemotherapy. High-quality papers concerning the entire range of bone and soft tissue sarcomas in both adults and children, including Kaposi"s sarcoma, are published as well as preclinical and animal studies. This journal provides a central forum for the description of advances in diagnosis, assessment and treatment of this rarely seen, but often mismanaged, group of patients.