Christopher Dobson, 1949-2019: Mentor, Friend, Scientist Extraordinaire.

IF 12.1 1区 生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY Annual review of biochemistry Pub Date : 2020-06-20 Epub Date: 2020-04-28 DOI:10.1146/annurev-biochem-011520-105226
Carol V Robinson
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引用次数: 2

Abstract

It is impossible to do justice in one review article to a researcher of the stature of Christopher Dobson. His career spanned almost five decades, resulting in more than 870 publications and a legacy that will continue to influence the lives of many for decades to come. In this review, I have attempted to capture Chris's major contributions: his early work, dedicated to understanding protein-folding mechanisms; his collaborative work with physicists to understand the process of protein aggregation; and finally, his later career in which he developed strategies to prevent misfolding. However, it is not only this body of work but also the man himself who inspired an entire generation of scientists through his patience, ability to mentor, and innate generosity. These qualities remain a hallmark of the way in which he conducted his research-research that will leave a lasting imprint on science.

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克里斯托弗·多布森,1949-2019:导师、朋友、非凡的科学家。
一篇评论文章不可能公正地评价Christopher Dobson这样的研究人员。他的职业生涯跨越了近50年,发表了870多篇文章,他的遗产将在未来几十年继续影响许多人的生活。在这篇综述中,我试图抓住Chris的主要贡献:他的早期工作,致力于理解蛋白质折叠机制;他与物理学家合作研究蛋白质聚集的过程;最后,在他后来的职业生涯中,他制定了防止错误折叠的策略。然而,通过他的耐心、指导能力和天生的慷慨,不仅是他的研究成果,也是他本人激励了整整一代科学家。这些品质仍然是他进行研究的方式的标志,这些研究将在科学界留下持久的印记。
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来源期刊
Annual review of biochemistry
Annual review of biochemistry 生物-生化与分子生物学
CiteScore
33.90
自引率
0.00%
发文量
31
期刊介绍: The Annual Review of Biochemistry, in publication since 1932, sets the standard for review articles in biological chemistry and molecular biology. Since its inception, these volumes have served as an indispensable resource for both the practicing biochemist and students of biochemistry.
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