Data Analysis and Classification of Autism Spectrum Disorder Using Principal Component Analysis.

Q1 Biochemistry, Genetics and Molecular Biology Advances in Bioinformatics Pub Date : 2020-01-07 eCollection Date: 2020-01-01 DOI:10.1155/2020/3407907
Ammar I Shihab, Faten A Dawood, Ali H Kashmar
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引用次数: 15

Abstract

Autism spectrum disorder (ASD) is an early developmental disorder characterized by mutation of enculturation associated with attention deficit disorder in the visual perception of emotional expressions. An estimated one in more than 100 people has autism. Autism affects almost four times as many boys than girls. Data analysis and classification of ASD is still challenging due to unsolved issues arising from many severity levels and range of signs and symptoms. To understanding the functions which involved in autism, neuroscience technology analyzed responses to stimuli of autistic audio and video. The study focuses on analyzing the data set of adults and children with ASD using practical component analysis method. To satisfy this aim, the proposed method consists of three main stages including: (1) data set preparation, (2) Data analysis, and (3) Unsupervised Classification. The experimental results were performed to classify adults and children with ASD. The classification results in adults give a sensitivity of 78.6% and specificity of 82.47%, while the classification results in children give a sensitivity of 87.5% and specificity of 95.7%.

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用主成分分析法分析自闭症谱系障碍的数据及分类。
自闭症谱系障碍(Autism spectrum disorder, ASD)是一种早期发育障碍,其特征是与情绪表达视觉感知中的注意缺陷障碍相关的文化适应突变。据估计,每100人中就有1人患有自闭症。受自闭症影响的男孩几乎是女孩的四倍。由于许多严重程度和体征和症状范围未解决的问题,ASD的数据分析和分类仍然具有挑战性。为了了解自闭症所涉及的功能,神经科学技术分析了自闭症音频和视频的刺激反应。本研究主要采用实用成分分析法对成人和儿童ASD的数据集进行分析。为了实现这一目标,本文提出的方法包括三个主要阶段,包括:(1)数据集准备,(2)数据分析和(3)无监督分类。根据实验结果对成人和儿童ASD进行分类。成人分类结果敏感性为78.6%,特异性为82.47%,儿童分类结果敏感性为87.5%,特异性为95.7%。
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来源期刊
Advances in Bioinformatics
Advances in Bioinformatics Biochemistry, Genetics and Molecular Biology-Biochemistry, Genetics and Molecular Biology (miscellaneous)
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