Pleomorphic Adenoma of the Parotid Gland and Ipsilateral Thyroid Incidentaloma: Report of A Rare Case With Review of Literature.

IF 1.1 Q4 MEDICINE, RESEARCH & EXPERIMENTAL Translational Medicine at UniSa Pub Date : 2020-05-31 eCollection Date: 2020-05-01
F Candelori, A Minni, A Greco, A Scarpa, C Cassandro, M Cavaliere, M Bisognox, E Cassandro, M de Vincentiis, M Ralli
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Abstract

Background: Pleomorphic adenomas are benign tumors of the salivary glands that mainly affect the lower pole of the superficial lobe of the parotid gland. The term "pleomorphic" refers to the epithelial and connective origin of the mass. The clinical presentation is typically that of asymptomatic swelling which increases in volume. Therapy consists in surgical removal of the tumor mass by parotidectomy with nerve preservation.

Case details: This clinical case describes an interesting case of pleomorphic adenoma of the parotid gland in a 62-year-old patient. The patient presented with a long history of an asymptomatic mildly worsening swelling of the left parotid region. The peculiarity of the clinical case is the dimension of the adenoma (9x5x9 cm) and the presence of a thyroid incidentaloma (TI), consisting of a thyroid multinodular goiter composed of nodules, the largest of which measured 8 cm in diameter. This mass dislocated the laryngotracheal axis, compressed the larynx and caused the reduction of the respiratory space, making orotracheal intubation difficult and determining the need to perform a tracheotomy.

Conclusion: Benign pleomorphic adenomas can potentially reach large sizes if untreated. Socio-economic problems may be the reason for late diagnosis.

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腮腺多形性腺瘤及同侧甲状腺偶发瘤1例报告并文献复习。
背景:多形性腺瘤是一种主要影响腮腺浅叶下极的涎腺良性肿瘤。“多形性”是指肿块的上皮和结缔组织起源。临床表现是典型的无症状肿胀,体积增加。治疗包括通过腮腺切除术切除肿瘤并保留神经。病例细节:本病例描述了一个有趣的腮腺多形性腺瘤病例,患者为62岁。患者表现出长期的无症状轻度恶化的左腮腺区肿胀史。临床病例的特点是腺瘤的尺寸(9x5x9cm)和甲状腺偶发瘤(TI)的存在,包括甲状腺多结节性甲状腺肿,其中最大的结节直径为8cm。该肿块使喉-气管轴脱位,压迫喉部,导致呼吸间隙缩小,使气管插管困难,需要行气管切开术。结论:良性多形性腺瘤如不及时治疗,可达到较大的体积。社会经济问题可能是晚期诊断的原因。
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Translational Medicine at UniSa
Translational Medicine at UniSa MEDICINE, RESEARCH & EXPERIMENTAL-
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