Epidemiologic and histologic characteristics of CNS lesions: a 20-year experience of a tertiary center in Lebanon.

Q1 Medicine CNS Oncology Pub Date : 2020-06-01 Epub Date: 2020-06-30 DOI:10.2217/cns-2020-0001

Roland Eid, Stephanie Hage, Ingrid Antonios, Rita Moussa, Makram Khoury, Fady Ghassan Haddad, Hampig Raphael Kourie, Carole Kesrouani, Claude Ghorra, Gerard Abadjian, Joseph Kattan

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引用次数: 2

Abstract

Aim: Report the epidemiologic and histologic characteristics of CNS lesions in the Lebanese population. Methods: We conducted a retrospective study evaluating 2025 CNS lesions diagnosed between 1998 and 2017 in the pathology laboratory of a Lebanese tertiary center. Results: 52.2% of patients were men with a median age of 50 years. The most frequent symptoms were epilepsy (22.5%), headache (20.6%) and motor impairment (19.9%). 90.7% of tumors were primary. Lung (35.6%) and breast (16.5%) were the most frequent primaries of metastases. 46.2% of primary CNS tumors were glial, predominantly astrocytic (56.4%), and (42.5%) were nonglial, predominantly meningeal tumors (58%). Conclusion: Compared with Western literature, the Lebanese population is characterized by a younger age of onset of brain tumors, a lower rate of meningiomas and a higher rate of gliomas.

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中枢神经系统病变的流行病学和组织学特征:黎巴嫩三级中心20年的经验。

目的:报道黎巴嫩人群中中枢神经系统病变的流行病学和组织学特征。方法:我们进行了一项回顾性研究，评估了1998年至2017年在黎巴嫩三级中心病理实验室诊断的2025例中枢神经系统病变。结果:52.2%的患者为男性，中位年龄50岁。最常见的症状是癫痫(22.5%)、头痛(20.6%)和运动障碍(19.9%)。90.7%为原发肿瘤。肺(35.6%)和乳腺(16.5%)是最常见的转移原发灶。46.2%的原发性中枢神经系统肿瘤为神经胶质细胞，以星形细胞为主(56.4%)，42.5%为非神经胶质细胞，以脑膜肿瘤为主(58%)。结论:与西方文献相比，黎巴嫩人群的特点是脑肿瘤发病年龄更年轻，脑膜瘤发病率较低，胶质瘤发病率较高。

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