Validity and reliability of the Patient Health Questionnaire-8 in Swedish for individuals with systemic sclerosis.

IF 2.9 3区医学 Q2 RHEUMATOLOGY Rheumatology International Pub Date : 2020-10-01 Epub Date: 2020-07-13 DOI:10.1007/s00296-020-04641-1

Malin Mattsson, Gunnel Sandqvist, Roger Hesselstrand, Annica Nordin, Carina Boström

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引用次数: 9

Abstract

Background: Depressive symptoms are common in rheumatic diseases and influence patients' quality of life. The Patient Health Questionnaire-9 (PHQ-9), which assesses symptoms of depression, is valid in English in patients with systemic sclerosis (SSc). However, the measurement properties of the PHQ-8 (short version of the PHQ-9) have not been evaluated in Swedish patients with SSc.

Objective: To investigate different aspects of validity and reliability of the PHQ-8 in Swedish (PHQ-8 Swe) for individuals with SSc.

Methods: A total of 101 patients with SSc participated. Content validity was evaluated via interviews of 11 patients and 10 health professionals. Construct validity, internal consistency test-retest reliability, and floor/ceiling effects were evaluated in 90 patients.

Results: Content validity was satisfactory, but some linguistic adjustments were made. Confirmatory factor analysis supported a better fit for a two-factor structure. Moderate-to-strong correlations were found between the PHQ-8 Swe and scleroderma HAQ including VAS (r_s = 0.4-0.7); Multidimensional Assessment of Fatigue (r_s = 0.7); RAND-36 subscales (r_s = - 0.5 to - 0.8); and lung disease severity (Medsger scores) (r_s = 0.4). There were weak correlations (r_s = <0.4) between the PHQ-8 Swe and modified Rodnan skin score; and vascular, heart, and kidney disease severity. Cronbach's alpha was 0.85, corrected item-to-total correlations were >0.40, and the ICC for the total score was 0.83. No floor/ceiling effects were found.

Conclusion: The PHQ-8 Swe has satisfactory content validity and sufficient reliability in patients with in majority limited SSc. It is more strongly associated with self-reported disability, pain, disease interferences with daily activities, fatigue, and quality of life than with disease severity, except for a moderate association with lung severity.

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瑞典患者健康问卷-8对系统性硬化症患者的效度和信度

背景:抑郁症状在风湿性疾病中很常见，影响患者的生活质量。患者健康问卷-9 (PHQ-9)，用于评估抑郁症状，在系统性硬化症(SSc)患者中是有效的英文版本。然而，PHQ-8 (PHQ-9的简写版本)的测量特性尚未在瑞典SSc患者中进行评估。目的:探讨瑞典语PHQ-8量表(PHQ-8 Swe)在SSc患者中的不同效度和信度。方法:共101例SSc患者参与。通过对11名患者和10名卫生专业人员的访谈来评估内容效度。对90例患者进行结构效度、内部一致性测试-重测信度和下限/上限效应评估。结果:内容效度满意，但在语言上做了一些调整。验证性因子分析支持更好地适合双因素结构。PHQ-8 Swe与硬皮病HAQ(包括VAS)存在中至强相关性(rs = 0.4 ~ 0.7);多维疲劳评价(rs = 0.7);RAND-36子量表(rs = - 0.5 ~ - 0.8);肺部疾病严重程度(Medsger评分)(rs = 0.4)。存在弱相关性(rs = 0.40)，总分的ICC为0.83。没有发现地板/天花板效应。结论:PHQ-8 Swe在大多数局限性SSc患者中具有满意的内容效度和足够的信度。它与自我报告的残疾、疼痛、疾病对日常活动的干扰、疲劳和生活质量的相关性比与疾病严重程度的相关性更强，除了与肺部严重程度的中度相关性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Rheumatology International 医学-风湿病学

CiteScore

7.30

自引率

5.00%

发文量

191

审稿时长

16. months

期刊介绍： RHEUMATOLOGY INTERNATIONAL is an independent journal reflecting world-wide progress in the research, diagnosis and treatment of the various rheumatic diseases. It is designed to serve researchers and clinicians in the field of rheumatology. RHEUMATOLOGY INTERNATIONAL will cover all modern trends in clinical research as well as in the management of rheumatic diseases. Special emphasis will be given to public health issues related to rheumatic diseases, applying rheumatology research to clinical practice, epidemiology of rheumatic diseases, diagnostic tests for rheumatic diseases, patient reported outcomes (PROs) in rheumatology and evidence on education of rheumatology. Contributions to these topics will appear in the form of original publications, short communications, editorials, and reviews. "Letters to the editor" will be welcome as an enhancement to discussion. Basic science research, including in vitro or animal studies, is discouraged to submit, as we will only review studies on humans with an epidemological or clinical perspective. Case reports without a proper review of the literatura (Case-based Reviews) will not be published. Every effort will be made to ensure speed of publication while maintaining a high standard of contents and production. Manuscripts submitted for publication must contain a statement to the effect that all human studies have been reviewed by the appropriate ethics committee and have therefore been performed in accordance with the ethical standards laid down in an appropriate version of the 1964 Declaration of Helsinki. It should also be stated clearly in the text that all persons gave their informed consent prior to their inclusion in the study. Details that might disclose the identity of the subjects under study should be omitted.