Pesticide Risk and Recurrent Pregnancy Loss in Females of Subhumid Region of India.

Akancha Pandey, Shyam Pyari Jaiswar, Nasreen Ghazi Ansari, Sujata Deo, Pushplata Sankhwar, Shriya Pant, Sushil Upadhyay
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引用次数: 9

Abstract

Objective: The objective of this study is to determine the level of pesticides and their role in cases of recurrent pregnancy loss (RPL).

Materials and methods: This was designed as a case-control study. Gas chromatography was used to characterize the pesticide level in 70 cases and 70 controls. Case refers to women with RPL, whereas controls refer to women with full-term delivery.

Results: A higher level of pesticide, namely beta-hexachlorocyclohexane, malathion, chlorpyrifos, and fenvalerate was found in the case group as compared to control group (P < 0.05).

Conclusions: The present study suggests that high exposure of pesticide (organochlorine and organophosphates) may increase the risk of RPL in females of the subhumid region of India.

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印度半湿润地区女性农药风险与复发性妊娠损失。
目的:本研究的目的是确定农药水平及其在复发性妊娠丢失(RPL)病例中的作用。材料和方法:本研究为病例对照研究。采用气相色谱法测定了70例病例和70例对照病例的农药残留量。病例指的是RPL的妇女,而对照组指的是足月分娩的妇女。结果:病例组农药残留量-六氯环己烷、马拉硫磷、毒死蜱、氰戊酸均高于对照组(P < 0.05)。结论:目前的研究表明,农药(有机氯和有机磷)的高暴露可能会增加印度半湿润地区女性RPL的风险。
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