First Do No Harm: A Cautious, Risk-adapted Approach to Testicular Cancer Patients.

Reviews in urology Pub Date : 2020-01-01
Hersh M Trivedi, Nirmish Singla, John Lafin, David Fetzer, Payal Kapur, Aditya Bagrodia
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Abstract

Current guidelines regarding treatment for germ-cell tumors (GCTs) emphasizes cautious progression focusing on stage-specific treatments. Presented herein is the case of a 30-year-old man who, through monitoring of serum alpha-fetoprotein (AFP) levels and surveillance imaging, avoided excessive treatment. This case demonstrates how an experienced clinician, familiar with natural history of GCTs, can appropriately classify level of risk and allow a patient to preserve natural fertility. Furthermore, we highlight the potential for miRNA analysis in staging and management of GCTs. This case serves to underscore the importance of acting with caution in the pursuit of the best outcome for our patients.

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首先不伤害:一个谨慎的,风险适应睾丸癌患者的方法。
目前关于生殖细胞肿瘤(gct)治疗的指南强调谨慎的进展,侧重于特定阶段的治疗。本文报告一位30岁男性患者,通过监测血清甲胎蛋白(AFP)水平和监测成像,避免了过度治疗。本病例表明,经验丰富的临床医生,熟悉gct的自然病史,可以适当地分类风险水平,并允许患者保留自然生育能力。此外,我们强调了miRNA分析在gct分期和管理中的潜力。这个病例强调了在为患者追求最佳结果时谨慎行事的重要性。
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