Seroprevalence of Rift Valley Fever and West Nile Fever in Cattle in Gambella Region, South West Ethiopia.

Abstract

Introduction: Rift Valley fever (RVF) and West Nile fever (WNF) are re-emerging mosquito-borne zoonotic diseases that cause public health and economic crises. Ethiopia shares borders with South Sudan and Kenya, where these diseases are often documented. The free movement of animals and humans across these borders expects to increase the spread of these diseases. The current study was conducted to assess the occurrence of these diseases in the Gambella region of Ethiopia.

Methodology: We collected a total of 368 cattle serum samples from the Lare district on the border of South Sudan and measured the presence of IgG antibody against RVF and WNF virus infections using enzyme-linked immunosorbent assays (ELISA).

Results: The prevalence of anti-RVF virus IgG antibody was 7.6% (95% CI: 5.3-10.82%), while that of anti-WNF virus IgG antibody was 5.4% (95% CI: 3.52-8.29%). In this study higher seroprevalence of IgG antibodies to RVF virus infection was observed comparing to the WNF virus in cattle. There was no significant association between the prevalence and the cattle age, sex or sampled locations.

Conclusion: The detection of IgG antibody to RVF and WNF virus infections in the Gambella region warrants further study of active case findings and the dynamics of transmission.