Potential Diagnostic Systems for Coronavirus Detection: a Critical Review.

IF 3.7 3区生物学 Q1 BIOCHEMICAL RESEARCH METHODS Biological Procedures Online Pub Date : 2020-09-01 eCollection Date: 2020-01-01 DOI:10.1186/s12575-020-00134-4

Elena Ekrami, Mahdi Pouresmaieli, Fatemeh Barati, Sahar Asghari, Farzad Ramezani Ziarani, Parvin Shariati, Matin Mamoudifard

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引用次数: 12

Abstract

Abstract: Currently there are no effective anti-viral drugs for SARS-CoV-2, so the primary line of defense is to detect infected cases as soon as possible. The high rate of contagion for this virus and the highly nonspecific symptoms of the disease (Coronovirus disease 2019, (Covid-19)) that it causes, such as respiratory symptoms, cough, dyspnea, fever, and viral pneumonia, require the urgent establishment of precise and fast diagnostic tests to verify suspected cases, screen patients, and conduct virus surveillance. Nowadays, several virus detection methods are available for viral diseases, which act on specific properties of each virus or virus family, therefore, further investigations and trials are needed to find a highly efficient and accurate detection method to detect and prevent the outcomes of the disease. Hence, there is an urgent need for more and precise studies in this field. In this review, we discussed the properties of a new generation of coronaviruses (SARS-CoV-2) following routine virus detection methods and proposed new strategies and the use of potential samples for SARS-CoV-2 detection.

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冠状病毒检测的潜在诊断系统:综述

摘要:目前还没有针对SARS-CoV-2的有效抗病毒药物，因此，尽快发现感染病例是第一道防线。该病毒的高感染率及其引起的高度非特异性症状(2019冠状病毒病(Covid-19))，如呼吸道症状、咳嗽、呼吸困难、发烧和病毒性肺炎，迫切需要建立精确和快速的诊断检测方法，以核实疑似病例、筛查患者并开展病毒监测。目前，针对病毒性疾病已有多种病毒检测方法，这些方法作用于每种病毒或病毒科的特异性，因此需要进一步的研究和试验，以找到一种高效、准确的检测方法来发现和预防疾病的后果。因此，迫切需要在这一领域进行更多、更精确的研究。在本文中，我们讨论了新一代冠状病毒(SARS-CoV-2)在常规病毒检测方法之后的特性，并提出了新的检测策略和潜在样本的使用。图形化的简介:

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Biological Procedures Online 生物-生化研究方法

CiteScore

10.50

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： iological Procedures Online publishes articles that improve access to techniques and methods in the medical and biological sciences. We are also interested in short but important research discoveries, such as new animal disease models. Topics of interest include, but are not limited to: Reports of new research techniques and applications of existing techniques Technical analyses of research techniques and published reports Validity analyses of research methods and approaches to judging the validity of research reports Application of common research methods Reviews of existing techniques Novel/important product information Biological Procedures Online places emphasis on multidisciplinary approaches that integrate methodologies from medicine, biology, chemistry, imaging, engineering, bioinformatics, computer science, and systems analysis.