Bevacizumab as a treatment option for choroidal neovascularisation due to large optic nerve drusen in a 14-year-old girl.

GMS ophthalmology cases Pub Date : 2020-08-06 eCollection Date: 2020-01-01 DOI:10.3205/oc000160
Nils Alexander Steinhorst, Martin Spitzer, Christos Skevas
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Abstract

Purpose: To report the effects of a single intravitreous injection of bevacizumab for the treatment of secondary choroideal neovascularisation due to large optic disc drusen. Methods: A 14-year-old female patient with painless loss of vision in one eye presented with unusually large optic disc drusen and juxtapapillary choroidal neovascularisation with subretinal hemorrhage. She was treated with a single intravitreous injection of bevacizumab. Results: Visual acuity increased from 20/100 to 20/25 within 4 weeks after injection and remained at this level during the 12-month follow-up period. Conclusions: Bevacizumab is a possible primary treatment option for secondary choroidal neovascularisation due to large optic disc drusen in children as an alternative to other more invasive or complex procedures.

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贝伐单抗作为治疗14岁女孩视神经萎缩所致脉络膜新生血管的选择。
目的:报道单次玻璃体内注射贝伐单抗治疗视盘肥大引起的继发性脉络膜新生血管的效果。方法:1例14岁女性无痛性失明患者,以视盘异常肿大、乳头旁脉络膜新生血管形成伴视网膜下出血为主要表现。她接受了单次玻璃体内注射贝伐单抗的治疗。结果:注射后4周内视力由20/100提高到20/25,随访12个月视力维持在20/100水平。结论:贝伐单抗是儿童视盘过大致继发性脉络膜新生血管形成的主要治疗选择,可替代其他更具侵入性或更复杂的手术。
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