Effect of Combined Herbal Capsule Menohelp on Hot Flashes and Night Sweats in Postmenopausal Women: A Single-Blind Randomized Controlled Trial.

Arezoo Shayan, Seyedeh Zahra Masoumi, Farideh Kazemi, Khodayar Oshvandi
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Abstract

Objectives: Hot flashes and night sweats are the most common and annoying consequences of menopause. The present study aimed to investigate the effect of a combined herbal capsule (black cohosh, soy, potato, chaste tree, and burdock) on hot flashes and night sweats in postmenopausal women.

Methods: The present study was a randomized clinical trial conducted on postmenopausal women who were referred to Hamadan health centers in 2018-2019. The patients were distributed randomly in two groups of 85 individuals using the permuted block technique. The intervention group received the Menohelp capsule 550 mg twice daily for eight weeks and those in the control group received placebo. Data was obtained using a demographic questionnaire and a night sweat checklist one week before and eight weeks after the intervention. Data analysis was done using Stata 13.

Results: Data analysis revealed that means of hot flashes duration, frequency and intensity did not significantly decrease in the postintervention phase as compared to the pre-intervention phase in both the groups (P > 0.05). Comparative analyses of frequency and intensity of night sweats in the two groups revealed that both variables decreased after intervention with the Menohelp capsule (P < 0.05).

Conclusions: This study revealed that combined herbal medicine (Menohelp) was effective in reducing the frequency and intensity of night sweats. Therefore, it can be used to reduce night sweats in postmenopausal women.

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复方止疼药胶囊对绝经后妇女潮热盗汗的影响:一项单盲随机对照试验。
目的:潮热和盗汗是更年期最常见和最恼人的后果。本研究旨在研究一种联合草药胶囊(黑升麻、大豆、土豆、贞德树和牛蒡)对绝经后妇女潮热和盗汗的影响。方法:本研究是一项随机临床试验,对2018-2019年转诊到哈马丹健康中心的绝经后妇女进行研究。采用排列阻滞技术将患者随机分为两组,每组85人。干预组服用Menohelp胶囊550毫克,每天两次,持续8周,对照组服用安慰剂。数据是在干预前一周和干预后八周通过人口统计问卷和盗汗检查表获得的。使用Stata 13进行数据分析。结果:数据分析显示,干预后两组患者潮热持续时间、频率和强度均较干预前无显著降低(P > 0.05)。两组患者盗汗频率和盗汗强度的比较分析显示,经Menohelp胶囊干预后,两组患者盗汗频率和盗汗强度均降低(P < 0.05)。结论:本研究显示复方中草药(Menohelp)可有效降低盗汗的频率和强度。因此,它可以用于减少绝经后妇女的盗汗。
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