The Influence of Co-Occurring Substance Use on the Effectiveness of Opiate Treatment Programs According to Intervention Type.

IF 5.2 2区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Epidemiologic Reviews Pub Date : 2020-01-31 DOI:10.1093/epirev/mxaa005
Courtney T Blondino, Mirinda Ann Gormley, DaShaunda D H Taylor, Elizabeth Lowery, James S Clifford, Benjamin Burkart, Whitney C Graves, Juan Lu, Elizabeth C Prom-Wormley
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引用次数: 7

Abstract

This systematic review describes the influence of co-occurring substance use on the effectiveness of opiate treatment programs. MEDLINE/PubMed, Embase, PsychINFO, and the Cumulative Index to Nursing and Allied Health Literature were searched from database inception to November 28, 2018, to identify eligible opioid treatment studies in the United States that assessed the relationship between co-occurring substance use and treatment outcome (i.e., opioid abstinence and treatment retention). A total of 34 eligible studies were included. Overall, co-occurring substance use was associated with negative treatment outcomes regardless of intervention type. However, patterns varied by substance and intervention type. In particular, co-occurring use of cocaine or marijuana with opioids was associated with reduced treatment retention and opioid abstinence regardless of intervention type. Co-occurring use of amphetamines, compared with no use or reduced use of amphetamines, decreased treatment retention. Co-occurring use of alcohol was both positively and negatively associated with treatment outcomes. One study reported a significant positive association between sedative use and opioid abstinence. Generally, findings suggest that combined interventions reported better health outcomes compared with pharmacological or behavioral intervention studies alone. The findings of this review emphasize the need to comprehensively study and address co-occurring substance use to improve opiate treatment programs.

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同时发生物质使用对阿片治疗方案干预类型有效性的影响。
本系统综述描述了共同发生的物质使用对阿片类药物治疗方案有效性的影响。从数据库建立到2018年11月28日,检索MEDLINE/PubMed、Embase、PsychINFO以及护理和联合健康文献累积索引,以确定美国符合条件的阿片类药物治疗研究,这些研究评估了共存物质使用与治疗结果(即阿片类药物戒断和治疗保留)之间的关系。共纳入34项符合条件的研究。总体而言,无论干预类型如何,共同发生的物质使用与负面治疗结果相关。然而,模式因物质和干预类型而异。特别是,可卡因或大麻与阿片类药物同时使用与治疗保留率降低和阿片类药物戒断有关,无论干预类型如何。与不使用或减少使用安非他明相比,同时使用安非他明降低了治疗效果。同时使用酒精与治疗结果呈正相关和负相关。一项研究报告了镇静剂使用与阿片类药物戒断之间的显著正相关。总的来说,研究结果表明,与单独的药物或行为干预研究相比,联合干预报告了更好的健康结果。本综述的结果强调需要全面研究和解决共同发生的物质使用,以改善阿片类药物治疗方案。
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来源期刊
Epidemiologic Reviews
Epidemiologic Reviews 医学-公共卫生、环境卫生与职业卫生
CiteScore
8.10
自引率
0.00%
发文量
10
期刊介绍: Epidemiologic Reviews is a leading review journal in public health. Published once a year, issues collect review articles on a particular subject. Recent issues have focused on The Obesity Epidemic, Epidemiologic Research on Health Disparities, and Epidemiologic Approaches to Global Health.
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