Quality of Life Structural Equation Model for Patients With Amyotrophic Lateral Sclerosis.

Abstract

Purpose: The aim of the study was to propose and test a quality of life model among Korean patients with amyotrophic lateral sclerosis (ALS) using structural equation modeling.

Design: A cross-sectional study was performed.

Methods: Data from 184 patients with ALS were collected from two university hospitals in Seoul and Busan, South Korea, between June and December 2018.

Findings: The modified model indices indicated adequate data fit. Quality of life predictors were social support, physical functional status, depression, and general health perception.

Conclusion: This study improved the understanding of quality of life for Korean patients with ALS, including complex direct and indirect relationships among quality of life factors.

Clinical relevance: Depression was identified as the most influential factor in this population; hence, early assessment and timely intervention for depression are essential for better quality of life in patients with ALS.