The effects of genetic background on exercise performance in Drosophila.

IF 4.7 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2020-03-01 Epub Date: 2020-10-26 DOI:10.1080/19336934.2020.1835329
Deena Damschroder, Kristin Richardson, Tyler Cobb, Robert Wessells
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Abstract

The use of the Drosophila model for studying the broad beneficial effects of exercise training has grown over the past decade. As work using Drosophila as an exercise model becomes more widespread, the influence of genetic background on performance should be examined in order to better understand its influence on assessments used to quantitatively measure and compare exercise phenotypes. In this article, we review the various methods of exercise training Drosophila, and the performance of different wild-type Drosophila strains on various physiological assessments of exercise response. We conclude by summarizing the performance trends of commonly used strains.

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遗传背景对果蝇运动表现的影响
在过去十年中,利用果蝇模型来研究运动训练的广泛有益影响的情况越来越多。随着使用果蝇作为运动模型的工作越来越广泛,应研究遗传背景对表现的影响,以便更好地了解其对用于定量测量和比较运动表型的评估的影响。在本文中,我们回顾了果蝇运动训练的各种方法,以及不同野生型果蝇品系在运动反应的各种生理评估中的表现。最后,我们总结了常用品系的表现趋势。
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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
期刊介绍: ACS Applied Bio Materials is an interdisciplinary journal publishing original research covering all aspects of biomaterials and biointerfaces including and beyond the traditional biosensing, biomedical and therapeutic applications. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrates knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important bio applications. The journal is specifically interested in work that addresses the relationship between structure and function and assesses the stability and degradation of materials under relevant environmental and biological conditions.
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