Lupus Vulgaris and Lichen Scrofulosorum with Disseminated Tuberculosis.

Nnenna Uzunma Okoh, T Nnaji, Chinwe L Onyekonwu, Chika Mary Emeka
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引用次数: 1

Abstract

Cutaneous tuberculosis (CTB) represents only 1%-2% of extrapulmonary forms of tuberculosis (TB). CTB can present in the isolation or coexist with pulmonary and disseminated forms of TB. Pathologically confirmed lupus vulgaris (LV) coexisting with lichen scrofulosorum with disseminated TB is presented and discussed. A 12-year-old boy presented with 2 years history of slowly progressive facial plaque and multiple skin colored papules on the neck. Tuberculin skin test was positive with a reading of > 20 mm. Histopathology revealed ulcerated areas with impetiginisation and keratopurulent debris. The entire skin showed pseudoepitheliomatous hyperplasia with numerous granulomas in the superficial dermis consisting of Langhans-type multinucleated macrophages. Lesions responded to anti-tuberculosis therapy (ATT) with residual facial scar. LV and lichen scrofulosurum are two forms of CTB which rarely occurs together. This case is being presented to highlight the occurrence of this rare presentation and the need to institute ATT to prevent scarring.

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寻常性狼疮、阴囊地衣伴播散性结核。
皮肤结核(CTB)仅占肺外结核(TB)的1%-2%。CTB可以单独出现,也可以与肺和播散性结核病共存。病理证实寻常性狼疮(LV)并发阴囊苔藓与播散性结核提出和讨论。一个12岁的男孩提出了2年的历史缓慢进展的面部斑块和颈部多个皮肤颜色丘疹。结核菌素皮肤试验阳性,读数> 20mm。组织病理学显示溃疡区伴脓疱化和角化脓性碎片。全皮肤可见假上皮瘤增生,真皮浅层可见大量肉芽肿,由朗汉斯型多核巨噬细胞组成。病变对抗结核治疗(ATT)有反应,伴有残留的面部疤痕。LV和阴囊苔藓是CTB的两种形式,很少同时发生。提出这个病例是为了强调这种罕见表现的发生,以及建立ATT以防止瘢痕形成的必要性。
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