Evaluation of Anthelminthic Activity of Tropical Taniferous Plant Extracts Against Haemonchus contortus.

IF 1.7 Q2 VETERINARY SCIENCES Veterinary medicine (Auckland, N.Z.) Pub Date : 2020-10-20 eCollection Date: 2020-01-01 DOI:10.2147/VMRR.S225717

Mastewal Birhan, Tilahun Gesses, Ambaye Kenubih, Haileyesus Dejene, Muluken Yayeh

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引用次数: 2

Abstract

Introduction: The present trial aimed to investigate invitro anthelminthic activities of selected tropical tanniferous plant extract on egg hatchability and larval development inhibition of Haemonchus contortus in sheep. In view of that, three tropical tanniferous plants Rhus glutinosa, Syzygium guineensa and Albizia gumifera, were selected based on their relative high content of condensed tannins.

Methods: In this study, eggs were collected from artificially infected with H. contortus. Then the egg was directly subjected to invitro assay with these condensed tannin-enriched extracts using egg hatchability assay and inhibition of larval development assay.

Results: The result showed that extracts from all three tropical tanniferous plants demonstrated statistically significant (P < 0.05) dosedependent inhibition of both egg hatchability and larval development. According to IC₅₀ and IC₉₀ values, the condensed tannin-enriched extracts inhibiting egg hatching and larval development most potently were Rhus glutinosa followed in descending order of activity by Syzygium guineensa and Albizia gumifera.

Discussion: The result of this study showed that these condensed tanninenriched extracts were effective in inhibiting egg hatchability as well as larval development. Therefore, condensed tannin might be recommended as one of the options for the control of H. contortus in sheep.

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热带蕨类植物提取物对弯血螨的驱虫活性评价。

前言:本试验旨在研究精选热带单宁植物提取物对绵羊卵孵化率和扭曲血蜱幼虫发育抑制的体外灭虫活性。鉴于此，选择了3种热带单宁植物Rhus glutinosa、Syzygium guinesa和Albizia gumifera，它们的缩合单宁含量相对较高。方法:采集人工感染弯纹夜蛾虫卵。然后将浓缩的富含单宁的提取物直接用于卵的体外孵化试验和幼虫发育抑制试验。结果:三种热带单宁植物提取物对虫卵孵化率和幼虫发育的抑制作用均有显著的剂量依赖性(P < 0.05)。从IC50和IC90值来看，浓缩富集单宁提取物对卵孵化和幼虫发育的抑制作用最大的是芦笋，抑制作用由大到小依次为豚草和合肥草。讨论:本研究结果表明，这些浓缩的富含单宁的提取物可以有效地抑制卵的孵化率和幼虫的发育。因此，浓缩单宁可能被推荐作为控制绵羊弯弯菌的选择之一。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Veterinary medicine (Auckland, N.Z.)

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16 weeks