Time to treatment initiation and outcomes in high-grade glioma patients in rehabilitation: a retrospective cohort study.

Q1 Medicine CNS Oncology Pub Date : 2020-12-01 Epub Date: 2020-10-28 DOI:10.2217/cns-2020-0018

Kwanza T Warren, Linxi Liu, Yang Liu, Myla S Strawderman, Ali H Hussain, Heather M Ma, Michael T Milano, Nimish A Mohile, Kevin A Walter

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引用次数: 3

Abstract

Aims: To investigate wait time (WT) for chemoradiation and survival in post-op high-grade glioma (HGG) patients admitted to inpatient rehabilitation compared with those discharged home. Materials & methods: A total of 291 HGG patients (14.4% grade III and 84.9% grade IV) were included in this retrospective cohort study. Patients were grouped by disposition following surgery. Results: Median length of stay was longer in acute inpatient rehabilitation facility (AIRF) patients (10d) compared with patients discharged home (3d). AIRF admission was associated with higher odds of excessive treatment delay. Median survival for AIRF patients less than for patients discharged home (42.9 vs 72.71 weeks). WT was not associated with survival even after adjusting for prognostic factors. Conclusion: HGG patients discharged to rehabilitation facilities have longer length of stay, longer WT and shorter survival compared with patients discharged home.

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康复治疗中高级别胶质瘤患者的治疗起始时间和预后:一项回顾性队列研究。

目的:比较住院康复的高级别胶质瘤(HGG)术后患者与出院患者的放化疗等待时间和生存率。材料与方法:本回顾性队列研究共纳入291例HGG患者(III级14.4%，IV级84.9%)。患者按术后处置进行分组。结果:急性住院康复设施(AIRF)患者的中位住院时间(10d)比出院回家的患者(3d)更长。AIRF入院与过度治疗延迟的几率较高相关。AIRF患者的中位生存期低于出院患者(42.9周vs 72.71周)。即使在调整预后因素后，WT也与生存率无关。结论:HGG患者在康复机构的住院时间更长，WT更长，生存时间更短。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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