{"title":"Stem cells: a new way of therapy for cardiovascular disorders.","authors":"Rabia Amjad, Isha Ishtiaq, Noor Fatima","doi":"10.21037/sci-2019-048","DOIUrl":null,"url":null,"abstract":"Cardiovascular disorder affects the overall health of an individual and hence the quality of life. Stem cell therapy involves the use of stem cells widely used to treat different conditions. People having severe cardiovascular disorder can be treated with stem cells by generating heart muscles, stimulating the growth of blood vessels and by the secretion of different growth factors. Different types of stem cells are used for cardiac repair. Adipose stem cells and induced pluripotent stem cells are better options for increasing the survival rate. In this review we will discuss different types of stem cells, their activation pathway, generation, hurdles in transplantation and how to overcome them and their applications.","PeriodicalId":21938,"journal":{"name":"Stem cell investigation","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2020-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7715658/pdf/sci-07-2019-048.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Stem cell investigation","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.21037/sci-2019-048","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2020/1/1 0:00:00","PubModel":"eCollection","JCR":"Q1","JCRName":"Biochemistry, Genetics and Molecular Biology","Score":null,"Total":0}
引用次数: 0
Abstract
Cardiovascular disorder affects the overall health of an individual and hence the quality of life. Stem cell therapy involves the use of stem cells widely used to treat different conditions. People having severe cardiovascular disorder can be treated with stem cells by generating heart muscles, stimulating the growth of blood vessels and by the secretion of different growth factors. Different types of stem cells are used for cardiac repair. Adipose stem cells and induced pluripotent stem cells are better options for increasing the survival rate. In this review we will discuss different types of stem cells, their activation pathway, generation, hurdles in transplantation and how to overcome them and their applications.
期刊介绍：
The Stem Cell Investigation (SCI; Stem Cell Investig; Online ISSN: 2313-0792) is a free access, peer-reviewed online journal covering basic, translational, and clinical research on all aspects of stem cells. It publishes original research articles and reviews on embryonic stem cells, induced pluripotent stem cells, adult tissue-specific stem/progenitor cells, cancer stem like cells, stem cell niche, stem cell technology, stem cell based drug discovery, and regenerative medicine. Stem Cell Investigation is indexed in PubMed/PMC since April, 2016.
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