High Prevalence of Depressive Symptoms Among Ugandan Patients with Rheumatoid Arthritis.

IF 1.7 Q3 RHEUMATOLOGY Open Access Rheumatology-Research and Reviews Pub Date : 2021-05-04 eCollection Date: 2021-01-01 DOI:10.2147/OARRR.S306503
Felix Bongomin, Barbra Natukunda, Maria Sekimpi, Ronald Olum, Joseph Baruch Baluku, Anthony Makhoba, Mark Kaddumukasa
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引用次数: 3

Abstract

Background: There is a scarcity of data on the burden of depression among Ugandans with rheumatoid arthritis (RA) patients. We aimed to screen for symptoms of depression, their severity and associated factors among patients with RA in Uganda.

Patients and methods: A descriptive, cross-sectional study was conducted between September and December 2020 at Mulago National Referral Hospital (MNRH) and Nsambya Hospital. Patients with RA were enrolled consecutively. Data on demographics, disease course and comorbidities and depression symptomatology were collected through an interviewer administered questionnaire. Symptoms of depression were screened for using the depression/anxiety dimension of the EuroQoL questionnaire.

Results: Forty-eight patients with a median age of 52 (IQR: 43.5-60.5) years were recruited in the study. The majority of the patients were female (91.7%, n=44). Twenty-nine patients (60.4%) had comorbidities with a median Charlson comorbidity score of 3 (IQR: 2-4). Overall, 70.8% (n=34) had depressive symptoms. Patients attending MNRH were more likely to have depressive symptoms (p=0.025). Significantly, patients with depressive symptoms were younger (p=0.027), had lower health index value (p<0.001), and lower overall self-reported health status (p=0.013). At binary logistic regression, patients at MNRH (crude odds ratio (COR): 4.32, 95% confidence interval (CI): 1.16-16.15, P=0.030), patients aged <52 years (COR: 5.24, 95% CI: 1.23-22.28, P=0.025) and those with mild RA (COR: 5.71, 95% CI: 1.15-28.35, P=0.033) were significantly more likely to have depressive symptoms. Increase in age (COR: 0.94, 95% CI: 0.89-0.99, P=0.025), and high visual analogue score (COR: 0.94, 95% CI: 0.89-0.99, P=0.013) were protective.

Conclusion: Depressive symptoms were common among RA patients in Uganda. Routine screening, diagnosis and management of depression is recommended among young patients to improve quality of life and patient outcomes.

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乌干达类风湿关节炎患者抑郁症状高发
背景:关于乌干达类风湿性关节炎(RA)患者抑郁负担的数据缺乏。我们的目的是筛查乌干达RA患者的抑郁症状、严重程度和相关因素。患者和方法:2020年9月至12月在穆拉戈国家转诊医院(MNRH)和Nsambya医院进行了一项描述性横断面研究。RA患者连续入组。通过采访者管理的问卷收集了人口统计学、病程、合并症和抑郁症状的数据。使用EuroQoL问卷的抑郁/焦虑维度筛选抑郁症状。结果:48例患者入组,中位年龄52岁(IQR: 43.5-60.5)岁。患者以女性居多(91.7%,n=44)。29例患者(60.4%)有合并症,Charlson合并症评分中位数为3 (IQR: 2-4)。总体而言,70.8% (n=34)有抑郁症状。参加MNRH的患者更有可能出现抑郁症状(p=0.025)。有抑郁症状的患者年龄更轻(p=0.027),健康指数值更低(p结论:乌干达RA患者普遍存在抑郁症状。建议对年轻患者进行抑郁症的常规筛查、诊断和管理,以改善患者的生活质量和预后。
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来源期刊
CiteScore
3.80
自引率
0.00%
发文量
34
审稿时长
16 weeks
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