Update in the Management of ANCA-Associated Vasculitis: Recent Developments and Future Perspectives.

IF 2.3 Q2 RHEUMATOLOGY International Journal of Rheumatology Pub Date : 2021-04-08 eCollection Date: 2021-01-01 DOI:10.1155/2021/5534851
Karla N Samman, Carolyn Ross, Christian Pagnoux, Jean-Paul Makhzoum
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Abstract

Significant progress has been made in the treatment of ANCA-associated vasculitides (AAV), notably in granulomatosis with polyangiitis and microscopic polyangiitis. Over the past few years, many innovative studies have changed the way we now induce and maintain remission in AAV; achieving remission while limiting treatment toxicity is the key. This article provides an in-depth, up-to-date summary of recent trials and suggests treatment algorithms for induction and maintenance of remission based on the latest guidelines. Future possible therapies in AAV will also be discussed.

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ANCA相关性血管炎管理的最新进展:最新进展与未来展望》。
ANCA相关血管炎(AAV)的治疗取得了重大进展,尤其是在多血管炎肉芽肿病和显微镜下多血管炎方面。过去几年中,许多创新性研究改变了我们现在诱导和维持 AAV 缓解的方法;实现缓解的同时限制治疗毒性是关键所在。本文对最近的试验进行了深入、最新的总结,并根据最新指南提出了诱导和维持缓解的治疗算法。文章还将讨论未来可能的 AAV 治疗方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
4.40
自引率
0.00%
发文量
9
审稿时长
24 weeks
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