The use of the ketogenic diet in the treatment of psychiatric disorders.

The Mental Health Clinician Pub Date : 2021-05-12 eCollection Date: 2021-05-01 DOI:10.9740/mhc.2021.05.211
Erika E Tillery, Katie D Ellis, Tiffaney B Threatt, Hannah A Reyes, Christopher S Plummer, Logan R Barney
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引用次数: 6

Abstract

Introduction: The ketogenic diet (KD) is a high-fat, low-carbohydrate, and moderate-protein diet that has shown benefit as a treatment in neurologic disorders and may serve as a therapeutic option in individuals with psychiatric disorders.

Methods: A search was conducted using EBSCOhost and PubMed databases for studies relating to ketogenic or low-carbohydrate diets and psychiatric disorders.

Results: A total of 32 experimental or observational studies were identified by initial search strategies, 14 of which met the criteria to be included in this analysis. Although specific diet formulations varied somewhat between studies, they all generally examined low-carbohydrate dietary intake with the goal of producing a ketotic state. The studies included in this review indicated the KD was beneficial in reducing symptoms associated with various psychiatric disorders.

Discussion: This review summarizes the available evidence regarding the efficacy of the ketogenic diet in psychiatric disease states. Data from the studies analyzed demonstrated a positive response in individuals who were able to remain on the diet, regardless of the disease state. However, there is a need for more data to clearly define the specific benefits the KD may provide.

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生酮饮食在精神疾病治疗中的应用。
生酮饮食(KD)是一种高脂肪、低碳水化合物和中等蛋白质的饮食,在神经系统疾病的治疗中显示出益处,也可以作为精神疾病患者的治疗选择。方法:使用EBSCOhost和PubMed数据库检索生酮或低碳水化合物饮食与精神疾病相关的研究。结果:通过初始检索策略共确定了32项实验或观察性研究,其中14项符合纳入本分析的标准。虽然具体的饮食配方在不同的研究中有所不同,但它们通常都是为了产生酮症状态而检查低碳水化合物的饮食摄入。本综述中纳入的研究表明,KD有助于减轻与各种精神疾病相关的症状。讨论:本综述总结了有关生酮饮食对精神疾病状态的疗效的现有证据。分析的研究数据表明,无论疾病状况如何,能够坚持饮食的人都有积极的反应。然而,需要更多的数据来明确定义KD可能提供的具体益处。
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