The Association between Age-Related Changes in Oral Neuromechanics and Alzheimer's Disease.

Advances in geriatric medicine and research Pub Date : 2021-01-01 Epub Date: 2021-04-27 DOI:10.20900/agmr20210011
Fritzie I Arce-McShane
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引用次数: 1

Abstract

The global population of 80 years and older is predicted to reach 437 million by 2050. As overall brain structure and function progressively degrades, older and younger adults show differences in sensorimotor performance and brain activity in the sensorimotor regions. Oral sensorimotor functions are an important area of focus in natural aging and Alzheimer's Disease (AD) because oral health issues are commonly found in both elderly and AD populations. While human behavioral studies on changes in oral sensorimotor functions abound, very little is known about their neuronal correlates in normal and pathological aging.

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老年口腔神经力学变化与阿尔茨海默病的关系
到2050年,全球80岁及以上人口预计将达到4.37亿。随着大脑整体结构和功能的逐渐退化,老年人和年轻人在感觉运动表现和感觉运动区域的大脑活动方面表现出差异。口腔感觉运动功能是自然衰老和阿尔茨海默病(AD)的一个重要领域,因为口腔健康问题在老年人和阿尔茨海默病人群中都很常见。虽然对口腔感觉运动功能变化的人类行为学研究很多,但对其在正常和病理性衰老中的神经元相关性知之甚少。
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