Keratoconus Epidemiology Presentations at Najran Province, Saudi Arabia.

IF 1.4 Q3 OPHTHALMOLOGY Clinical Optometry Pub Date : 2021-05-27 eCollection Date: 2021-01-01 DOI:10.2147/OPTO.S309651
Khaled Alzahrani, Ali Al-Rashah, Salem Al-Salem, Yahya Al-Murdif, Abdalaziz Al-Rashah, Alhassan Alrashah, Noura Al-Faify, Mohammed Ibrahim
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Abstract

Aim: Our study aims to produce an estimation of the keratoconus disease epidemiology and important demographic factors in disease presentation in Najran city in the south of Saudi Arabia.

Methods: Keratoconus patients between 9 and 29 years of age at the eye clinic of King Khaled General Hospital in Najran Province with a confirmed diagnosis of keratoconus were recruited over one year period. Visual acuity, keratometry, corneal thickness and demographic data were collected and analysed.

Results: The keratoconus prevalence in Najran Province was found to be 87.3 cases per 100,000 people with an incidence of 28.47 per 100,000 cases. The disease presented more frequently in male patients (67.9%) with a statistically significant difference in the mean age between genders (p=0.014). Most cases presented at a moderate stage, and almost half of the cases reported a family history of the disease. There were statistically significant differences in best visual acuity and corneal thickness between genders (p<0.05). The majority of the cases were managed with contact lenses (56.08%).

Conclusion: Genetic and environmental factors could have a substantial role in the increased rate of keratoconus presentation in Najran Province. Screening programmes should dedicate more attention to late presentation to improve prevention and early detection. More studies on keratoconus epidemiology in Saudi Arabia are needed.

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沙特阿拉伯纳杰兰省的角膜病流行病学报告。
目的:我们的研究旨在对沙特阿拉伯南部奈季兰市的角膜病流行病学和发病的重要人口学因素进行估计:在一年的时间里,在纳杰兰省哈立德国王总医院眼科门诊招募了 9 至 29 岁的角膜炎患者,并确诊为角膜炎。收集并分析了视力、角膜度数、角膜厚度和人口统计学数据:纳杰兰省的角膜病发病率为每 10 万人 87.3 例,发病率为每 10 万人 28.47 例。该病多发于男性患者(67.9%),男女患者的平均年龄差异有统计学意义(P=0.014)。大多数病例处于中度发病阶段,近一半病例报告有家族病史。性别间最佳视力和角膜厚度的差异有统计学意义(P结论:遗传和环境因素可能是导致纳杰兰省角膜炎发病率上升的重要原因。筛查计划应更多地关注晚期患者,以改善预防和早期发现。还需要对沙特阿拉伯的角膜病流行病学进行更多研究。
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来源期刊
Clinical Optometry
Clinical Optometry OPHTHALMOLOGY-
CiteScore
3.00
自引率
5.90%
发文量
29
审稿时长
16 weeks
期刊介绍: Clinical Optometry is an international, peer-reviewed, open access journal focusing on clinical optometry. All aspects of patient care are addressed within the journal as well as the practice of optometry including economic and business analyses. Basic and clinical research papers are published that cover all aspects of optics, refraction and its application to the theory and practice of optometry. Specific topics covered in the journal include: Theoretical and applied optics, Delivery of patient care in optometry practice, Refraction and correction of errors, Screening and preventative aspects of eye disease, Extended clinical roles for optometrists including shared care and provision of medications, Teaching and training optometrists, International aspects of optometry, Business practice, Patient adherence, quality of life, satisfaction, Health economic evaluations.
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