Protein Intake and Cognitive Function in Older Adults: A Systematic Review and Meta-Analysis.

IF 2.3 Q3 NUTRITION & DIETETICS Nutrition and Metabolic Insights Pub Date : 2021-06-04 eCollection Date: 2021-01-01 DOI:10.1177/11786388211022373
Hélio José Coelho-Júnior, Riccardo Calvani, Francesco Landi, Anna Picca, Emanuele Marzetti
{"title":"Protein Intake and Cognitive Function in Older Adults: A Systematic Review and Meta-Analysis.","authors":"Hélio José Coelho-Júnior,&nbsp;Riccardo Calvani,&nbsp;Francesco Landi,&nbsp;Anna Picca,&nbsp;Emanuele Marzetti","doi":"10.1177/11786388211022373","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>The present study investigated the association between protein intake and cognitive function in older adults.</p><p><strong>Methods: </strong>We performed a literature search with no restriction on publication year in MEDLINE, SCOPUS, CINAHL, AgeLine from inception up to October 2020. Observational studies that investigated as a primary or secondary outcome the association of protein intake and cognitive function in older adults aged ⩾60 years were included.</p><p><strong>Results: </strong>Nine cross-sectional studies that investigated a total of 4929 older adults were included in the qualitative analysis. Overall cognitive function was examined in 6 studies. Four investigations reported null associations and 2 studies found that older adults with a high protein intake had higher global cognitive function than their counterparts. Results from the meta-analysis suggested that there were no significant associations between protein consumption and global cognitive function in older adults, regardless of gender. Three studies investigated other cognitive domains. Memory and protein intake were significantly and positively correlated in all studies. In addition, visuospatial, verbal fluency, processing speed, and sustained attention were positively associated with protein consumption in 1 study each.</p><p><strong>Conclusion: </strong>No significant associations between protein intake and global cognitive function were observed in neither qualitative nor quantitative analyses. The association between protein consumption with multiple other cognitive domains were also tested. As a whole, 3 studies reported a positive and significant association between high protein intake and memory, while 1 study observed a significant and positive association with visuospatial, verbal fluency, processing speed, and sustained attention.</p>","PeriodicalId":19396,"journal":{"name":"Nutrition and Metabolic Insights","volume":"14 ","pages":"11786388211022373"},"PeriodicalIF":2.3000,"publicationDate":"2021-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/11786388211022373","citationCount":"6","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nutrition and Metabolic Insights","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/11786388211022373","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2021/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"NUTRITION & DIETETICS","Score":null,"Total":0}
引用次数: 6

Abstract

Introduction: The present study investigated the association between protein intake and cognitive function in older adults.

Methods: We performed a literature search with no restriction on publication year in MEDLINE, SCOPUS, CINAHL, AgeLine from inception up to October 2020. Observational studies that investigated as a primary or secondary outcome the association of protein intake and cognitive function in older adults aged ⩾60 years were included.

Results: Nine cross-sectional studies that investigated a total of 4929 older adults were included in the qualitative analysis. Overall cognitive function was examined in 6 studies. Four investigations reported null associations and 2 studies found that older adults with a high protein intake had higher global cognitive function than their counterparts. Results from the meta-analysis suggested that there were no significant associations between protein consumption and global cognitive function in older adults, regardless of gender. Three studies investigated other cognitive domains. Memory and protein intake were significantly and positively correlated in all studies. In addition, visuospatial, verbal fluency, processing speed, and sustained attention were positively associated with protein consumption in 1 study each.

Conclusion: No significant associations between protein intake and global cognitive function were observed in neither qualitative nor quantitative analyses. The association between protein consumption with multiple other cognitive domains were also tested. As a whole, 3 studies reported a positive and significant association between high protein intake and memory, while 1 study observed a significant and positive association with visuospatial, verbal fluency, processing speed, and sustained attention.

Abstract Image

Abstract Image

Abstract Image

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
老年人蛋白质摄入与认知功能:系统回顾和荟萃分析。
本研究调查了老年人蛋白质摄入与认知功能之间的关系。方法:在MEDLINE、SCOPUS、CINAHL、AgeLine中检索自成立至2020年10月的文献,不限制发表年份。观察性研究将年龄大于或等于60岁的老年人中蛋白质摄入量和认知功能的关联作为主要或次要结果进行调查。结果:定性分析包括9项横断面研究,共调查了4929名老年人。在6项研究中检查了整体认知功能。四项调查报告无关联,两项研究发现高蛋白摄入量的老年人比同龄人具有更高的全球认知功能。荟萃分析的结果表明,无论性别如何,老年人的蛋白质摄入量与整体认知功能之间没有显着关联。三项研究调查了其他认知领域。在所有的研究中,记忆力与蛋白质摄入量呈显著正相关。此外,在每项研究中,视觉空间、语言流畅性、处理速度和持续注意力都与蛋白质消耗呈正相关。结论:在定性和定量分析中均未观察到蛋白质摄入与整体认知功能之间的显著关联。蛋白质摄入与多种其他认知领域之间的关系也被测试。总体而言,3项研究报告了高蛋白摄入与记忆之间的显著正相关,而1项研究发现高蛋白摄入与视觉空间、语言流畅性、处理速度和持续注意力之间存在显著正相关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Nutrition and Metabolic Insights
Nutrition and Metabolic Insights NUTRITION & DIETETICS-
CiteScore
3.30
自引率
0.00%
发文量
27
审稿时长
8 weeks
期刊介绍: Nutrition and Metabolic Insights is a peer-reviewed, open-access online journal focusing on all aspects of nutrition and metabolism. This encompasses nutrition, including the biochemistry of metabolism, exercise and associated physical processes and also includes clinical articles that relate to metabolism, such as obesity, lipidemias and diabetes. It includes research at the molecular, cellular and organismal levels. This journal welcomes new manuscripts for peer review on the following topics: Nutrition, including the biochemistry of metabolism, Exercise and associated physical processes, Clinical articles that relate to metabolism, such as obesity, lipidemias and diabetes, Research at the molecular, cellular and organismal levels, Other areas of interest include gene-nutrient interactions, the effects of hormones, models of metabolic function, macronutrient interactions, outcomes of changes in diet, and pathophysiology.
期刊最新文献
Dietary Intake of Chromista Oil Alters Hepatic Metabolomic Profile of Mice With Excess Fat Mass. Impact of Nutritional Status on Chemotherapy Related Digestive Toxicity in Women With Breast Cancer. Dietary Flavonoid Intake and Risk of Mild Cognitive Impairment in the Elderly: A Case-Control Study. Effects of High-Carbohydrate and High-Fat Diets on Parasympathetic and Sympathetic Nervous Activities: An Experimental Study Using Heart Rate Variability. Hyperuricemia and Associated Factors in Adult Cardiac Patients in Western Oromia, Ethiopia.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1