{"title":"The effect of short-term spinal cord electrical stimulation on patients with postherpetic neuralgia and its effect on sleep quality.","authors":"Jinzhou Liu, Aimin Zhang, Xiaolong Ye, Xin H, Ruilin He, Zongbin Jiang","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>To investigate the effect of short-term spinal cord electrical stimulation (stSCS) on postherpetic neuralgia (PHN) and its effect on sleep quality in patients in Guangxi, China.</p><p><strong>Material and methods: </strong>160 patients with acute PHN patients were divided into a control group and an experimental group according to the random number table method, 80 cases each. The experimental group was implanted with percutaneous epidural electrodes and given short-term spinal cord electrical stimulation treatment, while the control group was treated with nerve block therapy to compare the efficacy and sleep quality of the two groups of patients in different periods. Pain Visual Analogue Scale (VAS) score and Pittsburgh Sleep Quality Index (PSQI) were used to evaluate the analgesic effect and sleep quality, respectively.</p><p><strong>Results: </strong>The patients in the experimental group had significantly lower visual analog scale (VAS) scores and Pittsburgh Sleep Quality Index (PSQI) scores at 1, 2, 3 d, 1 week, and 1 and 3 months after treatment than those in the control group [after treatment 3 months: (0.86±0.31) points to (2.97±0.55) points, (5.4±1.16) score to (7.46±1.27) score], the difference was statistically significant (both P<0.05), and VAS and PSQI scores of the two groups showed a significant downward trend with the increase of treatment time.</p><p><strong>Conclusion: </strong>The clinical effect of short-term spinal cord electrical stimulation on PHN is good, and it can play a rapid and effective relief effect on pain in patients. At the same time, it will effectively improve patient's sleep quality, with high safety.</p>","PeriodicalId":19098,"journal":{"name":"Neuro endocrinology letters","volume":"42 2","pages":"81-86"},"PeriodicalIF":0.6000,"publicationDate":"2021-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neuro endocrinology letters","FirstCategoryId":"3","ListUrlMain":"","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"ENDOCRINOLOGY & METABOLISM","Score":null,"Total":0}
引用次数: 0
Abstract
Objectives: To investigate the effect of short-term spinal cord electrical stimulation (stSCS) on postherpetic neuralgia (PHN) and its effect on sleep quality in patients in Guangxi, China.
Material and methods: 160 patients with acute PHN patients were divided into a control group and an experimental group according to the random number table method, 80 cases each. The experimental group was implanted with percutaneous epidural electrodes and given short-term spinal cord electrical stimulation treatment, while the control group was treated with nerve block therapy to compare the efficacy and sleep quality of the two groups of patients in different periods. Pain Visual Analogue Scale (VAS) score and Pittsburgh Sleep Quality Index (PSQI) were used to evaluate the analgesic effect and sleep quality, respectively.
Results: The patients in the experimental group had significantly lower visual analog scale (VAS) scores and Pittsburgh Sleep Quality Index (PSQI) scores at 1, 2, 3 d, 1 week, and 1 and 3 months after treatment than those in the control group [after treatment 3 months: (0.86±0.31) points to (2.97±0.55) points, (5.4±1.16) score to (7.46±1.27) score], the difference was statistically significant (both P<0.05), and VAS and PSQI scores of the two groups showed a significant downward trend with the increase of treatment time.
Conclusion: The clinical effect of short-term spinal cord electrical stimulation on PHN is good, and it can play a rapid and effective relief effect on pain in patients. At the same time, it will effectively improve patient's sleep quality, with high safety.
期刊介绍:
Neuroendocrinology Letters is an international, peer-reviewed interdisciplinary journal covering the fields of Neuroendocrinology, Neuroscience, Neurophysiology, Neuropsychopharmacology, Psychoneuroimmunology, Reproductive Medicine, Chronobiology, Human Ethology and related fields for RAPID publication of Original Papers, Review Articles, State-of-the-art, Clinical Reports and other contributions from all the fields covered by Neuroendocrinology
Letters.
Papers from both basic research (methodology, molecular and cellular biology, anatomy, histology, biology, embryology, teratology, normal and pathological physiology, biophysics, pharmacology, pathology and experimental pathology, biochemistry, neurochemistry, enzymology, chronobiology, receptor studies, endocrinology, immunology and neuroimmunology, animal physiology, animal breeding and ethology, human ethology, psychology and others) and from clinical research (neurology, psychiatry and child psychiatry, obstetrics and gynecology, pediatrics, endocrinology, immunology, cardiovascular studies, internal medicine, oncology and others) will be considered.
The Journal publishes Original papers and Review Articles. Brief reports, Special Communications, proved they are based on adequate experimental evidence, Clinical Studies, Case Reports, Commentaries, Discussions, Letters to the Editor (correspondence column), Book Reviews, Congress Reports and other categories of articles (philosophy, art, social issues, medical and health policies, biomedical history, etc.) will be taken under consideration.