A rare association between group A Streptococcus purpura fulminans and diffuse alveolar hemorrhage in a young girl: A case report

IF 1.3 4区 医学 Q3 PEDIATRICS Archives De Pediatrie Pub Date : 2021-08-01 DOI:10.1016/j.arcped.2021.04.012
E. Cousin , T. Gaillot , B. Ozanne , A. Ryckewaert , S. Dessard , O. Tirel , J.-L. Fausser
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Abstract

We report the case of a 7-year-old girl with septic shock and coagulopathy associated with purpura fulminans (PF) and diffuse alveolar hemorrhage (DAH) due to group A Streptococcus (GAS) infection identified with 16S ribosomal RNA analysis performed on the skin biopsy. GAS infection with PF associated with DAH is rare in healthy young children but pediatricians should be aware of this condition because of the poor prognosis. The initial treatment for circulatory failure and severe disseminated intravascular coagulation as well as the prompt initiation of antibiotic treatment may be crucial for the outcomes of S. pyogenes PF.

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A组暴发性紫癜链球菌与一年轻女孩弥漫性肺泡出血的罕见关联:1例报告
我们报告一例7岁女孩感染性休克和凝血功能障碍,并伴有暴发性紫癜(PF)和弥漫性肺泡出血(DAH),这是由于a组链球菌(GAS)感染引起的,在皮肤活检中通过16S核糖体RNA分析发现。GAS感染与PF合并DAH在健康幼儿中很少见,但由于预后不良,儿科医生应注意这种情况。循环衰竭和严重弥散性血管内凝血的初始治疗以及及时开始抗生素治疗可能对化脓性链球菌PF的预后至关重要。
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来源期刊
Archives De Pediatrie
Archives De Pediatrie 医学-小儿科
CiteScore
2.80
自引率
5.60%
发文量
106
审稿时长
24.1 weeks
期刊介绍: Archives de Pédiatrie publishes in English original Research papers, Review articles, Short communications, Practice guidelines, Editorials and Letters in all fields relevant to pediatrics. Eight issues of Archives de Pédiatrie are released annually, as well as supplementary and special editions to complete these regular issues. All manuscripts submitted to the journal are subjected to peer review by international experts, and must: Be written in excellent English, clear and easy to understand, precise and concise; Bring new, interesting, valid information - and improve clinical care or guide future research; Be solely the work of the author(s) stated; Not have been previously published elsewhere and not be under consideration by another journal; Be in accordance with the journal''s Guide for Authors'' instructions: manuscripts that fail to comply with these rules may be returned to the authors without being reviewed. Under no circumstances does the journal guarantee publication before the editorial board makes its final decision. Archives de Pédiatrie is the official publication of the French Society of Pediatrics.
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